science

Karin E. de Visser

Karin E. de Visser is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Karin E. de Visser rather than just read about it. In short: Karina Elizabeth de Visser (Karin de Visser, 1975), also named "Karin E. de Visser", is a researcher at the Netherlands Cancer Institute. Her research considers metastatic formation and how the immune system influences how people respond to cancer treatment.

Key takeaways

Karin E. de Visser belongs to science; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Karin E. de Visser to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Karin E. de Visser from memory before moving on to harder problems.

Reference excerpt

Karina Elizabeth de Visser (Karin de Visser, 1975), also named "Karin E. de Visser", is a researcher at the Netherlands Cancer Institute. Her research considers metastatic formation and how the immune system influences how people respond to cancer treatment.

Early life and education In 1998 De Visser obtained her master's degree in Biomedical Science at Leiden University (cum laude). De Visser was a postgraduate student at the Netherlands Cancer Institute, supervised by prof. dr. Ada Kruisbeek. In 2002 she got her PhD degree at the Vrije Universiteit Amsterdam with her thesis The impact of self-antigen expression on the CD8+ T cell repertoire: Implications for anti-tumor immunity. In 2003 she was appointed a postdoctoral fellow with Lisa Coussens at the University of California, San Francisco. Here she started working on the interaction between the adaptive and innate immune system. She spent two years in California, before returning to the Netherlands Cancer Institute where she started working on inflammation and carcinogenesis.

Research and career De Visser launched her independent career at the Netherlands Cancer Institute, where she started working on tumour biology and immunology. De Visser looks to understand how the immune system impacts the formation of metastasis and response to cancer treatment. In particular, De Visser has focussed on breast cancer, and how tumours can hijack the immune system to allow for metastatic spread. She also identified that the precise genetic make-up of breast cancer determines pro-metastatic inflammation. She works closely with Marleen Kok on translation of her findings to clinical environments, including looking to understand the landscape of breast cancer patients treated with checkpoint inhibitors.

Awards and honours 2014 European Research Council Consolidator Grant 2015 Beug Foundation Metastasis Research Prize 2016 Elected to the European Molecular Biology Organization 2019 Awarded a NWO-VICI grant 2021 Elected member of the European Molecular Biology Organization

Select publications Visser, Karin de (2002). The impact of self-antigen expression on the CD8+ T cell repertoire: Implications for anti-tumor immunity. s.l.: s.n. OCLC 66167703. Karin E. de Visser; Eichten A; Lisa M. Coussens (January 2006). "Paradoxical roles of the immune system during cancer development". Nature Reviews Cancer. 6 (1): 24–37. doi:10.1038/nrc1782. ISSN 1474-175X. PMID 16397525. Wikidata Q29614305. Karin E. de Visser; Jos Jonkers (1 January 2009). "Towards understanding the role of cancer-associated inflammation in chemoresistance". Current Pharmaceutical Design. 15 (16): 1844–1853. doi:10.2174/138161209788453239. ISSN 1381-6128. OCLC 5524179038. PMID 19519427. Wikidata Q37515888. Seth B. Coffelt; Kelly Kersten; Chris W Doornebal; et al. (30 March 2015). "IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis". Nature. 522 (7556): 345–348. doi:10.1038/nature14282. ISSN 1476-4687. PMC 4475637. PMID 25822788. Wikidata Q35763387. Seth B. Coffelt; Max D Wellenstein; Karin E. de Visser (10 June 2016). "Neutrophils in cancer: neutral no more". Nature Reviews Cancer. 16 (7): 431–446. doi:10.1038/nrc.2016.52. ISSN 1474-175X. PMID 27282249. Wikidata Q38860382.

References

Worked examples

Example 1 — a first encounter with Karin E. de Visser

Start with the simplest possible case. Write down what Karin E. de Visser claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Karin E. de Visser before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Karin E. de Visser ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Karin E. de Visser

In research: Karin E. de Visser appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Karin E. de Visser in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Karin E. de Visser is common in secondary-school and first-year university syllabi. It links to neighbouring topics Cancer researchers, Dutch women scientists, Living people, so understanding it makes those chapters shorter.
In everyday life: Look for Karin E. de Visser outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Karin E. de Visser in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Karin E. de Visser means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Karin E. de Visser out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Karin E. de Visser in simple terms?

Why does Karin E. de Visser matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Karin E. de Visser?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Karin E. de Visser.