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LILRA2

LILRA2 is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand LILRA2 rather than just read about it. In short: Leukocyte immunoglobulin-like receptor subfamily A member 2 (LILRA2, CD85H, ILT1) is a protein that in humans is encoded by the LILRA2 gene. Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells.

LILRA2 — main illustration
LILRA2 — illustration

Key takeaways

  • LILRA2 belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect LILRA2 to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of LILRA2 from memory before moving on to harder problems.

Reference excerpt

Leukocyte immunoglobulin-like receptor subfamily A member 2 (LILRA2, CD85H, ILT1) is a protein that in humans is encoded by the LILRA2 gene. Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.[supplied by OMIM]

Function LILRA2 senses microbially cleaved immunoglobulin to activate human myeloid cells.

See also Cluster of differentiation

References

Further reading

External links LILRA2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) PDBe-KB provides an overview of all the structure information available in the PDB for Human Leukocyte immunoglobulin-like receptor subfamily A member 2 (LILRA2) This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Illustrations

LILRA2 illustration
LILRA2 illustration
LILRA2 illustration
LILRA2 illustration
LILRA2 illustration

Worked examples

Example 1 — a first encounter with LILRA2

Start with the simplest possible case. Write down what LILRA2 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to LILRA2 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about LILRA2 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of LILRA2

In research
LILRA2 appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses LILRA2 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
LILRA2 is common in secondary-school and first-year university syllabi. It links to neighbouring topics Clusters of differentiation, Genes on human chromosome 19, Immunoglobulin superfamily, so understanding it makes those chapters shorter.
In everyday life
Look for LILRA2 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study LILRA2 in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what LILRA2 means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain LILRA2 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is LILRA2 in simple terms?

Leukocyte immunoglobulin-like receptor subfamily A member 2 (LILRA2, CD85H, ILT1) is a protein that in humans is encoded by the LILRA2 gene. Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and…

Why does LILRA2 matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study LILRA2?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on LILRA2.

Tags

  • Clusters of differentiation
  • Genes on human chromosome 19
  • Immunoglobulin superfamily
  • Immunology stubs
  • Membrane protein stubs

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