Lysophosphatidic acid receptor 2 also known as LPA2 is a protein that in humans is encoded by the LPAR2 gene. LPA2 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).
Function This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins.
Interactions LPAR2 has been shown to interact with TRIP6.
Evolution
Paralogues Source:
LPAR1 LPAR3 S1PR1 S1PR5 S1PR4 S1PR2 S1PR3 GPR6 GPR3 GPR12 MC4R MC5R CNR1 MC3R CNR2 MC1R GPR119 MC2R
See also Lysophospholipid receptor
References
Further reading
External links "Lysophospholipid Receptors: LPA2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2008-12-05. Lysophospholipid+receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.






