LY03017, also known as LPM-526000133, is a serotonin 5-HT2 receptor antagonist which is under development for the treatment of schizophrenia and Alzheimer's psychosis. It acts specifically as a dual serotonin 5-HT2A receptor inverse agonist and serotonin 5-HT2C receptor antagonist. The drug is under development by Luye Pharma Group in China. As of December 2025, it is in phase 1 clinical trials. The chemical structure of LY03017 does not yet appear to have been disclosed.
See also Serotonin 5-HT2A receptor antagonist List of investigational antipsychotics
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