In enzymology, a lactosylceramide beta-1,3-galactosyltransferase (EC 2.4.1.179) is an enzyme that catalyzes the chemical reaction
UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-R ⇌ {\displaystyle \rightleftharpoons } UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-R Thus, the two substrates of this enzyme are UDP-galactose and D-galactosyl-1,4-beta-D-glucosyl-R, whereas its two products are UDP and D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-R. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase. Other names in common use include uridine diphosphogalactose-lactosylceramide, and beta1->3-galactosyltransferase.
References
Bailly P, Piller F, Cartron JP (1988). "Characterization and specific assay for a galactoside beta-3-galactosyltransferase of human kidney". Eur. J. Biochem. 173 (2): 417–22. doi:10.1111/j.1432-1033.1988.tb14015.x. PMID 3129295.
