Lalita Ramakrishnan (born 1959) is an Indian-born American microbiologist who is known for her contributions to the understanding of the biological mechanism of tuberculosis. As of 2019 she serves as a professor of Immunology and Infectious Diseases at the University of Cambridge, where she is also a Wellcome Trust Principal Research Fellow and a practicing physician. Her research is conducted at the MRC Laboratory of Molecular Biology (MRC LMB), where she serves as the Head of the Molecular Immunity Unit of the Department of Medicine embedded at the MRC LMB. Working with Stanley Falkow at Stanford, she developed the strategy of using Mycobacterium marinum infection as a model for tuberculosis. Her work has appeared in a number of journals, including Science, Nature, and Cell. In 2018 and 2019 Ramakrishnan coauthored two influential papers in the British Medical Journal (BMJ) arguing that the widely accepted estimates of the prevalence of latent tuberculosis—estimates used as a basis for allocation of research funds—are far too high. She is married to Mark Troll, a physical chemist.
Early life and education Ramakrishnan was born in 1959 in Baroda (now Vadodara) and grew up there. Her parents were both scientists as is her brother, Nobel laureate Venki Ramakrishnan. When Ramakrishnan was a child, her mother had three bouts of spinal tuberculosis. As a high school student, Ramakrishnan excelled at math and physics. Ramakrishnan began attending medical school at age 17, which is "not atypical in India, where specialized training begins shortly after high school." In 1983, she graduated with a Bachelor of Medicine degree in Vadodara from Baroda Medical College. After taking an elective course in advanced immunology, Ramakrishnan decided to study immunology. In 1990, she graduated from Tufts University with a PhD in Immunology. She then became the first foreign graduate of the medical residency program at Tufts-New England Medical Center. After completing a fellowship in Infectious Diseases at the University of California at San Francisco hospitals, including San Francisco General Hospital (now Zuckerberg San Francisco General Hospital and Trauma Center), Ramakrishnan completed postdoctoral work in Stanley Falkow's lab at Stanford University, where she developed the strategy of using Mycobacterium marinum infection in zebrafish as a model for tuberculosis.
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