Lanthanum triflate is a complex inorganic compound of lanthanum, fluorine, carbon, sulphur, and oxygen with the chemical formula (CF3SO3)3La. This is the lanthanum salt of trifluoromethanesulphonic acid.
Synthesis Lanthanum triflate is typically synthesized by reacting lanthanum oxide with 50% aqueous trifluoromethanesulfonic acid under heating.
La2O3 + 6HOTf → 2La(OTf)3 + 3H2O
Physical properties The compound forms white to gray-white solid. It is soluble in water; partially soluble in tetrahydrofuran (THF) and dichloromethane; sparingly soluble in diethyl ether; and insoluble in hexane. Like other lanthanide triflates, lanthanum triflate is a Lewis acid, but unlike other Lewis acids like AlCl3, it is stable in water.
Uses The compound serves as an efficient standalone catalyst for the direct synthesis of various amides from esters and amines under gentle reaction conditions.
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