biology

Laurent Degos

Laurent Degos is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Laurent Degos rather than just read about it. In short: Laurent Degos, Professor of Haematology at the University of Paris, was born on July 9, 1945, in Paris (75008) from Robert Degos (1904–1987) medical doctor, Professor of Dermatology and Monique Lortat Jacob (1916–1999), third of four children, an older brother Jean Denis (1937–2001) Professor of Neurology, Claude François Professor of Neurology (born 1939) and a younger sister Bernadette Flamant (born 1947). He was…

Key takeaways

Laurent Degos belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Laurent Degos to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Laurent Degos from memory before moving on to harder problems.

Reference excerpt

Laurent Degos, Professor of Haematology at the University of Paris, was born on July 9, 1945, in Paris (75008) from Robert Degos (1904–1987) medical doctor, Professor of Dermatology and Monique Lortat Jacob (1916–1999), third of four children, an older brother Jean Denis (1937–2001) Professor of Neurology, Claude François Professor of Neurology (born 1939) and a younger sister Bernadette Flamant (born 1947). He was married to Françoise Fouchard (hepatologist) on 16 December 1971 with whom he had three children Juliette Barbarin (lawyer at Total), Cecile Petit-Degos (scenographer), and Vincent Degos (Professor of Anesthesia Resuscitation) and nine grandchildren (Arthur, Maylis, Paul Barbarin, Jules, Zelie, Tom Petit and Oscar, Augustin, Felix Degos). The Degos family is from Mugron (Landes) with several generations of country medical doctors: Jean Baptiste (1797–1859), Alfred (1840–1925) and Louis (1873–1928), his grandfather. He is a corresponding member of the French Academy of sciences.

Biography Laurent Degos obtained his doctorate of medicine in 1976 and his doctorate of University in 1973 at the Paris Diderot University France. He was a resident of the Paris Hospitals (1967) and obtained his Master's degree in "Management of health research" in 1983 at Harvard T.H. Chan School of Public Health (US). Laurent Degos, a close collaborator of Jean Dausset (Nobel Prize winner 1980) since 1969, succeeded him in 1980 as head of the immunogenetics laboratory (Inserm). He was elected Councillor for International workshops of Histocompatibility (Los Angeles 1980). He discovered genes and alleles of the histocompatibility complex, made innovations in formal genetics (binding imbalance) and population genetics (selection, genetic distance). He was Vice-President of the Institut Curie (2011–2014) and Vice-President of the Institut Pasteur (2014–2016). As a research manager, Laurent Degos has been elected to several evaluation commissions (Inserm, CNRS, National Council of Universities), Director of the University Institute, International Advisor (Histocompatibility), President of international congresses (EHA 1994, ISQUA 2010, Health and Tech Conference 2017). His position in national agencies gave him the opportunity to be called upon in various institutions as an advisor. In addition, he is interested in the new generation, writing science books for children, textbooks for students, co-founder and board member of the MURS, (science and society). Having been Director of the Inserm U 93 Unit (1981–1993), Director of the University Institute of Haematology (1993–2003 Univ. Paris), Director of the Doctoral School of Biology and Biotechnology (1993–2003) he is also involved in current debates on scientific integrity. Laurent Degos has a broad disciplinary field in medical sciences (molecular biology, cell biology, clinical trials) and studies transverse disciplines (immunology, oncology, hematology, transplantation, public health). He has collectively taken over the concepts and developments as president of public (Delegate for Clinical Research Ile de France) or private (Genset, IEPS) research councils. He currently sits on the boards of directors and committees of SMEs: "2nd opinion" (chairman of the scientific committee), Metafora (strategy) and Care Insight (board of directors), e-Sana (strategy). He has also demonstrated his ability to obtain interdisciplinary and multidisciplinary research for policy within the framework of the Bioalliance of European Medical Societies and has successfully joined European Member States by co-founding Eunet HTA for the study of comparative efficacy of health products and leading Eunet PAS for patient safety research. Laurent Degos has experience of scientific advice and political responsibilities at the Council of Europe (Histocompatibility 1980), DG Sanco (Eunet HTA 2005–2011 EuNetPAS 2007–2011) and DG RTD (steering committee and leader of the WG1 SPH 2015–). He has demonstrated authority and independence as guest scientific advisor for the preparation of the US Affordable Care Act (ACA) on comparative efficacy research, representing France alongside three other members from the United Kingdom, Germany and Australia, and as guest member of the nomination committee in China for the CAS institute for translational medicine (Canton). He was also a member of the High Level Group on Health at the OECD and President of the Sino-French Foundation for Science and Technology (FFCSA Chinese - Chinese Academy of Science and French Academy of sciences (2011–2017).

Scientific work Laurent Degos has defined platelet glycoproteins recently used as targets for anticoagulation. His original and anti-dogmatic vision made it possible to discover how to transform a malignant cell into a normal cell (1982) with medical doctors in Shanghai (China) including Wang Zhen Yi and Chen Zhu in the case of the most severe acute leukaemia (acute promyelocytic leukaemia) which is now easily and permanently cured in all "standard" cases with two natural products, a vitamin A derivative and arsenic, without chemotherapy or bone marrow transplantation, opening a new approach to cancer treatment (malignant cell differentiation treatment, personalized medicine, precision treatments, targeted treatments) that has won several international awards, including the General Motors Prize, the most prestigious award for cancer research. He also continued his research in social, economic and human sciences as President of the French High Authority on Health (2005–2011) where he headed a college of 8 executive members, 400 high-level collaborators, 3,000 experts (62,000K€) to evaluate health technology, to make recommendations for good practices, certify healthcare establishments, and provide medical and economic advice, after having been President of the Afssaps (Medicines Agency) (2003–2005) and President of the French Transplant Establishment (2003–2005) (transformed into the French Biomedicine Agency in 2004). He is the author of several hundred publications.

Main books He is the author of many books including :

Quelle politique de Santé pour demain ? Éloge de l'erreur Santé : Sortir des crises Les organes de mon corps Mon corps : cent mille milliards de cellules Cloner est-il immoral ?

Honours and awards

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Illustrations

Worked examples

Example 1 — a first encounter with Laurent Degos

Start with the simplest possible case. Write down what Laurent Degos claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Laurent Degos before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Laurent Degos ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Laurent Degos

In research: Laurent Degos appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Laurent Degos in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Laurent Degos is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1945 births, Academic staff of the University of Paris, Cell biologists, so understanding it makes those chapters shorter.
In everyday life: Look for Laurent Degos outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Laurent Degos in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Laurent Degos means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Laurent Degos out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Laurent Degos in simple terms?

Why does Laurent Degos matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Laurent Degos?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Laurent Degos.