The leukotriene (LT) receptors are G protein-coupled receptors that bind and are activated by the leukotrienes. They include the following proteins:
Leukotriene B4 receptors (BLTRs) – bind to and are activated by LTB4: BLT1 (Leukotriene B4 receptor 1) – LTB4R BLT2 (Leukotriene B4 receptor 2) – LTB4R2 Cysteinyl leukotriene receptors (CysLTRs) – bind to and are activated by LTC4, LTD4, and LTE4: CysLT1 (Cysteinyl leukotriene receptor 1) – CYSLTR1 CysLT2 (Cysteinyl leukotriene receptor 2) – CYSLTR2 The recently elucidated CysLTE, represented by GPR99/OXGR1, may constitute a third CysLTR.
See also Eicosanoid receptor Oxoeicosanoid receptor Prostaglandin receptor Thromboxane receptor
References
External links IUPHAR GPCR Database – Leukotriene receptors Leukotriene+Receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)