In enzymology, a linoleate isomerase (EC 5.2.1.5) is an enzyme that catalyzes the chemical reaction
9-cis,12-cis-octadecadienoate ⇌ {\displaystyle \rightleftharpoons } 9-cis,11-trans-octadecadienoate Hence, this enzyme has one substrate, 9-cis,12-cis-octadecadienoate, and one product, 9-cis,11-trans-octadecadienoate. This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is linoleate Delta12-cis-Delta11-trans-isomerase. This enzyme is also called linoleic acid isomerase. This enzyme participates in linoleic acid metabolism.
References
Kepler CR, Tove SB (1967). "Biohydrogenation of unsaturated fatty acids. 3. Purification and properties of a linoleate delta-12-cis, delta-11-trans-isomerase from Butyrivibrio fibrisolvens". J. Biol. Chem. 242 (24): 5686–92. doi:10.1016/S0021-9258(18)99355-5. PMID 5633396.
