science

List of clinical trial registries

List of clinical trial registries is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand List of clinical trial registries rather than just read about it. In short: The list of clinical trial registries includes any clinical trial registration system managed by a government or other organization. Global registry The World Health Organization's International Clinical Trials Registry Platform (ICTRP) acts as a voluntary coordinating body for many international registries, including many of those listed below.

Key takeaways

List of clinical trial registries belongs to science; place it in that map before memorising details.
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Reproduce the core statement of List of clinical trial registries from memory before moving on to harder problems.

Reference excerpt

The list of clinical trial registries includes any clinical trial registration system managed by a government or other organization.

Global registry The World Health Organization's International Clinical Trials Registry Platform (ICTRP) acts as a voluntary coordinating body for many international registries, including many of those listed below.

National and regional registries

Africa The Pan-African clinical trials registry (PACTR) is available at pactr.org. It is funded by the European and Developing Countries Clinical Trials Partnership (EDCTP) and operates out of the South African Cochrane Centre (Cochrane Collaboration) based at the South African Medical Research Council. PACTR contributes data to the WHO's ICTRP.

Australia and New Zealand Australia and New Zealand share the ANZCTR registry located at: anzctr.org.au. Registering trials with the ANZCTR is voluntary. It is publicly owned and managed by a non-profit organization and is funded by an enabling grant from Australia's National Health and Medical Research Council (NHMRC).

Brazil Brazil has a registry (Registro Brasileiro de Ensaios Clínicos, ReBEC): ensaiosclinicos.gov.br. ReBEC is a project of the Brazilian Ministry of Health, the Panamerican Health Organization (PAHO) and the Oswaldo Cruz Foundation (FIOCRUZ).

Canada The Canadian Institutes of Health Research (CIHR) participates with the ISRCTN.

China China's clinical trial registry is called ChiCTR: chictr.org.cn. It is available in Mandarin Chinese and English. It was established in October 2005. It participates in the WHO's ICTRP.

Cuba Cuba's clinical registry is the RPCEC (Cuban Public Registry of Clinical Trials).

European Union

EudraCT is a database of all clinical trials conducted in the European Union since 1 May 2004. Initially a non-public database, it was launched for the public as EU Clinical Trials Register in March 2011.

Germany Germany's clinical trials registry, the DRKS, is available at drks.de. The DRKS is an open access, free of charge online register for clinical trials and is available both in English and German. DRKS is part of the WHO's ICTRP. The DRKS works with two partner registries in Germany, DeReG (German Registry for Somatic Gene-Transfer Trials) and Clinical Trial Registry of the University Medical Center Freiburg.

India India's clinical trials registry is Clinical Trials Registry – India. CTRI is in English and it participates in the WHO's ICTRP.

Iran Iran's registry, the IRCT, is available at irct.ir. It is run and funded by the Iranian Ministry of Health and Medical Education.

Japan Japan has three registries that work as a network called the Japan Primary Registries Network (JPRN). Its search portal is hosted by the Japanese National Institute of Public Health. While the search portal is only available in Japanese, the three registries' sites are also available in English:

University Hospital Medical Information Network (UMIN CTR) Japan Pharmaceutical Information Center - Clinical Trials Information (JapicCTI) Japan Medical Association - Center for Clinical Trials (JMACCT CTR)

Netherlands The Netherlands registry participates with WHO and its website is trialregister.nl. Clinical trial data are available in English.

South Africa South Africa's Department of Health announced in November 2005, that clinical trials conducted in the country must be submitted to the South African National Clinical Trials Register located at: sanctr.gov. Clinical trial guidelines for South Africa are available at the Department of Health's official site.

South Korea South Korea's registry is Clinical Research Information Service (CRiS) and available at https://web.archive.org/web/20101121001837/http://ncrc.cdc.go.kr/cris/index.jsp. It is managed by the Korea Centers for Disease Control and Prevention and funded by South Korea's Ministry of Health and Welfare.

Sri Lanka The Sri Lanka Clinical Trials Registry (SLCTR) is available at slctr.lk. It is funded by the Sri Lanka Medical Association and managed by the Sri Lanka Clinical Trials Registry Committee.

United Kingdom The ISRCTN registry was launched in 2000. Originally ISRCTN stood for 'International Standard Randomised Controlled Trial Number'; however, the scope of the registry has widened beyond randomized controlled trials to include any study designed to assess the efficacy of health interventions in a human population. It registers both observational and interventional trials and content is curated by a team of expert editors.

United States

Clinical trials in the US are registered on clinicaltrials.gov. Clinicaltrials.gov is the largest clinical trials registry. Clinical trials conducted in the United States are required to be registered in the registry. Its registrations represent about 75% of what is available through the WHO portal (ICTRP). Problems of concordance between ClinicalTrials.gov records and published records have been identified for many protocol and results items. The registry traces back to the Health Omnibus Programs Extension Act of 1988 (HOPE or Public Law 100-607) which mandated the development of a database of AIDS Clinical Trials Information System. It would later be expanded under the Food and Drug Administration Modernization Act of 1997 (FDAMA or Public Act 105-115). The registry is run by the United States National Library of Medicine (NLM).

Other registries Clinical trial registries are also set up and managed by governmental organizations, non-governmental organizations, universities, as well as commercial and nonprofit entities. This includes pharmaceutical companies, international organizations, and health organizations. A list is available at http://www.circare.org/registries.htm. The IFPMA Clinical Trials Portal is a major pharmaceutical industry initiative designed to increase the transparency of clinical trials by providing a convenient "one-stop-shop" for published clinical trial information. It helps to fulfill the commitment made by the research-based pharmaceutical industry in its Joint Position on the Disclosure of Clinical Trial Information via Clinical Trial Registries and Databases. It is available here.

References

Worked examples

Example 1 — a first encounter with List of clinical trial registries

Start with the simplest possible case. Write down what List of clinical trial registries claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to List of clinical trial registries before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about List of clinical trial registries ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of List of clinical trial registries

In research: List of clinical trial registries appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses List of clinical trial registries in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: List of clinical trial registries is common in secondary-school and first-year university syllabi. It links to neighbouring topics Clinical trials, so understanding it makes those chapters shorter.
In everyday life: Look for List of clinical trial registries outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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Frequently asked questions

What is List of clinical trial registries in simple terms?

The list of clinical trial registries includes any clinical trial registration system managed by a government or other organization. Global registry The World Health Organization's International Clinical Trials Registry Platform (ICTRP) acts as a voluntary coordinating body for many international r…

Why does List of clinical trial registries matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study List of clinical trial registries?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on List of clinical trial registries.