This is a list of psychedelic drugs, also known as serotonergic psychedelics or classical hallucinogens. These drugs act specifically as serotonin 5-HT2A receptor agonists. They belong to three major structural families, including the tryptamines, phenethylamines, and lysergamides, although exceptions exist.
Tryptamines
No ring substitutions
4-Hydroxytryptamines
4-Phosphoryloxytryptamines
4-Acyloxytryptamines
5-Hydroxytryptamines
5-Acyloxytryptamines
5-Methoxytryptamines
Other ring substitutions
α-Alkyltryptamines
5-Methoxy-α-alkyltryptamines
Others N-DEAOP-Ts (e.g., N-DEAOP-NET, N-DEAOP-NMT, 5-MeO-N-DEAOP-NMT, 5-MeO-N-DEAOP-NET)
Structure undisclosed
Cyclized tryptamines
Unknown psychedelic activity β-Carbolines (e.g., 1-ethyl-6-hydroxytryptoline, 1-(2,4,5-trimethoxyphenyl)-6-chlorotryptoline)
Tryptamine bioisosteres
Unknown psychedelic activity Quinolinylethylamines (e.g., mefloquine)
Phenethylamines
Scalines
Thioscalines
Desoxyscalines 4-Desoxymescaline (desoxy, desoxymescaline)
Others
2C-x
2C-T-x
2C-O-x
Others
3C-x
DOx
Aleph-x (DOT-x)
TMA-2 and derivatives (Mxx)
Others
4C-x
Ψ-PEA
MDxx
FLY
Hemi/semi-FLY drugs
25x-NB (NBOMes)
25x-NBOMe
25x-NBOH
25x-NBF
Others
Others
Structure undisclosed
Cyclized phenethylamines
Unknown psychedelic activity Aporphines and noraporphines (e.g., glaucine, 11-methoxyasimilobine, 2-hydroxy-11-(2-methylallyl)oxynoraporphine)
Lysergamides
No substitutions
Amide-substituted lysergamides
6-Alkyllysergamides
1-Alkyllysergamides (prodrugs)
1-Acyllysergamides (prodrugs)
Others
Lysergamide bioisosteres
Others
Structure undisclosed
Natural sources
Tryptamines
Phenethylamines
Lysergamides
See also List of drugs List of hallucinogens List of entheogens List of entactogens List of designer drugs List of investigational hallucinogens and entactogens List of psychoactive drugs Psychedelic plants PiHKAL and TiHKAL List of psychedelic chemists List of psychedelic pharmaceutical companies
References

