Lithium propionate, also known as lithium propanoate, is a lithium salt of propionic acid with the chemical formula EtCOOLi. It is the lightest of the metal propionates.
Structure A solid−solid phase transition occurs, suggesting dimorphism despite the crystal system remaining monoclinic.
Preparation Lithium propionate can be prepared by treating a basic lithium salt such as lithium carbonate or lithium hydroxide with propionic acid.
Uses Lithium propionate is used in laboratory research. Like the closely related lithium acetate (LiOAc), lithium propionate is used as a buffer in certain cosmetic products. Lithium propionate has also been investigated in the development of electrodes, where secondary lithium electrodes were introduced in propylene carbonate. In organic synthesis, lithium propionate esters have been used to stereoselectively induce alternating methyl and methoxy moieties in α-β unsaturated esters through a Michael addition reaction.
Reactions Decomposition takes place via ketonization, yielding the symmetric ketone (3-pentanone) and lithium carbonate:
2Li(O2CEt) → Li2CO3 + Et(CO)Et
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