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Long-chain acyl-CoA dehydrogenase

Long-chain acyl-CoA dehydrogenase is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Long-chain acyl-CoA dehydrogenase rather than just read about it. In short: Long-chain acyl-CoA dehydrogenase (EC 1.3.8.8, palmitoyl-CoA dehydrogenase, palmitoyl-coenzyme A dehydrogenase, long-chain acyl-coenzyme A dehydrogenase, long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase, ACADL (gene).) is an enzyme with systematic name long-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase. This enzyme catalyses the following chemical reaction a long-chain acyl-CoA + electron-transfe…

Key takeaways

  • Long-chain acyl-CoA dehydrogenase belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Long-chain acyl-CoA dehydrogenase to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Long-chain acyl-CoA dehydrogenase from memory before moving on to harder problems.

Reference excerpt

Long-chain acyl-CoA dehydrogenase (EC 1.3.8.8, palmitoyl-CoA dehydrogenase, palmitoyl-coenzyme A dehydrogenase, long-chain acyl-coenzyme A dehydrogenase, long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase, ACADL (gene).) is an enzyme with systematic name long-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase. This enzyme catalyses the following chemical reaction

a long-chain acyl-CoA + electron-transfer flavoprotein ⇌ {\displaystyle \rightleftharpoons } a long-chain trans-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein This enzyme contains FAD as prosthetic group and participates in fatty acid metabolism and PPAR signaling pathway. Mitochondrial mutations in this enzyme may be associated with some forms of dilated cardiomyopathy.

References

External links Long-chain+acyl-CoA+dehydrogenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Worked examples

Example 1 — a first encounter with Long-chain acyl-CoA dehydrogenase

Start with the simplest possible case. Write down what Long-chain acyl-CoA dehydrogenase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Long-chain acyl-CoA dehydrogenase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Long-chain acyl-CoA dehydrogenase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Long-chain acyl-CoA dehydrogenase

In research
Long-chain acyl-CoA dehydrogenase appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Long-chain acyl-CoA dehydrogenase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Long-chain acyl-CoA dehydrogenase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 1.3.8, Flavoproteins, so understanding it makes those chapters shorter.
In everyday life
Look for Long-chain acyl-CoA dehydrogenase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study Long-chain acyl-CoA dehydrogenase in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Long-chain acyl-CoA dehydrogenase means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Long-chain acyl-CoA dehydrogenase out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Long-chain acyl-CoA dehydrogenase in simple terms?

Long-chain acyl-CoA dehydrogenase (EC 1.3.8.8, palmitoyl-CoA dehydrogenase, palmitoyl-coenzyme A dehydrogenase, long-chain acyl-coenzyme A dehydrogenase, long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase, ACADL (gene).) is an enzyme with systematic name long-chain acyl-CoA:electron-transfer flavopr…

Why does Long-chain acyl-CoA dehydrogenase matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Long-chain acyl-CoA dehydrogenase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Long-chain acyl-CoA dehydrogenase.

Tags

  • EC 1.3.8
  • Flavoproteins

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