Low anterior hairline is a dysmorphic feature in which the frontal hairline which defines the top and sides of the forehead is unusually low. This can mean that either the distance between the trichion (hairline) and glabella at the midline is more than 2 standard deviations below the mean, or that this distance is apparently (subjectively) decreased.
Conditions Low anterior hairline is seen in the following conditions and syndromes:
8q22.1 microdeletion syndrome Adams-Oliver syndrome 2 Agenesis of the corpus callosum with peripheral neuropathy ALG11-congenital disorder of glycosylation Barber-Say syndrome Blepharophimosis - intellectual disability syndrome, Verloes type Bohring-Opitz syndrome Cataract - congenital heart disease - neural tube defect syndrome Cerebellar atrophy, visual impairment, and psychomotor retardation Coffin-Siris syndrome 5 and 12 COG7 congenital disorder of glycosylation Congenital lactic acidosis, Saguenay-Lac-Saint-Jean type Cornelia de Lange syndrome 3 and 5 Craniosynostosis 6 Deficiency of alpha-mannosidase Deletion of long arm of chromosome 18 DOORS syndrome Dysmorphism-conductive hearing loss-heart defect syndrome Ectodermal dysplasia 13, hair/tooth type Fanconi anemia, complementation group S Focal facial dermal dysplasia type III Fontaine progeroid syndrome Hereditary spastic paraplegia 49 Intellectual disability, autosomal dominant 14, 42, and 52 KBG syndrome Lissencephaly 7 with cerebellar hypoplasia Megalocornea-intellectual disability syndrome MEGF8-related Carpenter syndrome Microcephaly, short stature, and impaired glucose metabolism 1 Muenke syndrome Nicolaides-Baraitser syndrome Pontocerebellar hypoplasia, IIA 17 Rubinstein-Taybi syndrome due to CREBBP mutations
Saethre-Chotzen syndrome SCARF syndrome Skin creases, congenital symmetric circumferential, 2 Spondyloepimetaphyseal dysplasia, Bieganski type Spondyloepimetaphyseal dysplasia, Genevieve type TCF12-related craniosynostosis Vertebral anomalies and variable endocrine and T-cell dysfunction Warburg Micro syndrome 2, 3, and 4 Zimmermann-Laband syndrome 1 and 3
See also High anterior hairline
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