Lufenuron is a chemical with insecticidal properties, belonging to the class of insecticides called insect growth regulators. It is a chitin synthesis inhibitor belonging to the benzoylurea class (IRAC group 15).
Applications
Veterinary Lufenuron is one of the two active ingredients in the flea, heartworm, and anthelmintic medicine milbemycin oxime/lufenuron (Sentinel). It was also the active ingredient in the previously-marketed veterinary flea control medication Program. Lufenuron is stored in the animal's body fat and transferred to adult fleas through the host's blood when they feed. Adult fleas transfer it to their growing eggs through their blood, and to hatched larvae feeding on their excrement. It does not kill adult fleas. Lufenuron inhibits the production of chitin in insects. Without chitin, a larval flea will never develop a hard outer shell (exoskeleton). With its inner organs exposed to air, the insect dies from dehydration soon after hatching or molting (shedding its old, smaller shell). Lufenuron is also used to fight fungal infections, since fungus cell walls are about one third chitin.
Agriculture Lufenuron is also sold as an agricultural pesticide for use against lepidopterans, eriophyid mites, and western flower thrips. It is an effective antifungal in plants.
References
External links Lufenuron in the Pesticide Properties DataBase (PPDB)



