Lymphomatoid papulosis (LyP) is a rare skin disorder.
Prevalence The overall prevalence rate of lymphomatoid papulosis is estimated at at least 1.2 cases per 1,000,000 population. This rare condition has only been studied in depth since 1968.
Presentation It can appear very similar to anaplastic large cell lymphoma. Type "A" is CD30 positive, while type "B" is CD30 negative. It has been described as "clinically benign but histologically malignant."
Treatment It may respond to methotrexate or PUVA.
Prognosis It can evolve into lymphoma.
See also Cutaneous T-cell lymphoma Parapsoriasis Secondary cutaneous CD30+ large cell lymphoma List of cutaneous conditions
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