Lysergic acid ethyl-2-hydroxyethylamide (LEO) is a serotonin receptor modulator of the lysergamide family related to lysergic acid diethylamide (LSD). It is the derivative of LSD in which one of its N-ethyl groups of LSD has been hydroxylated at the end or 2 position. It is also an active metabolite of LSD including in humans. LEO shows potent antiserotonergic activity and oxytocic activity in the isolated rat uterus in vitro similarly to LSD. In addition, it produced hyperthermia in rabbits in vivo similarly to LSD. LEO was first described in the scientific literature by 1974.
See also Substituted lysergamide LA-MeO Lysergic acid hydroxyethylamide (LSH) Ergometrine 13-Hydroxy-LSD
References
External links LEO - Isomer Design



