A lysophosphatidylserine is a lysophospholipid. Various lysophosphatidylserines trigger TLR 2. They can also modulate T cell function via suppression of Interleukin_2 (IL-2) production in CD4 T cells. They can also trigger mast cell degranulation. They interact with three G protein-coupled receptors (GPCRs), LPS1/GPR34, LPS2/P2Y10, and LPS3/GPR174. A recent study showed that lysophosphatidylserines do not stimulate normal leukocytes. They also enhances glucose transport, lowering blood glucose levels while leaving secretion of insulin unaffected.
References
External links Lysophosphatidylserine at the U.S. National Library of Medicine Medical Subject Headings (MeSH)