chemistry

Makhluf Haddadin

Makhluf Haddadin is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Makhluf Haddadin rather than just read about it. In short: Makhluf J. Haddadin (1935 – September 21, 2022) was a Jordanian chemistry professor at the American University of Beirut.

Key takeaways

Makhluf Haddadin belongs to chemistry; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Makhluf Haddadin to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Makhluf Haddadin from memory before moving on to harder problems.

Reference excerpt

Makhluf J. Haddadin (1935 – September 21, 2022) was a Jordanian chemistry professor at the American University of Beirut.

Biography Haddadin was born in Ma'in, Jordan in 1935. He won a full scholarship from the Jordanian Ministry of Education, to study chemistry at the American University of Beirut from which he graduated with a B.Sc. and an M.Sc. under the direction of Costas H. Issidorides. He then left for the University of Colorado Boulder, Colorado, USA where he received a Ph.D. degree in organic chemistry under the direction of Alfred Hassner. After two years of postdoctoral work under Louis Fieser at Harvard University, he joined the Faculty of Arts and Sciences at the American University of Beirut where he was a Professor of Chemistry. Haddadin served the American University of Beirut as Vice President for Academic Affairs (12 years), Acting Dean of the Faculty of Health Sciences (3.5 years), Chairman of the Chemistry Department (10 years), occasional Acting Dean of the Faculty of Arts and Sciences, Acting Deputy President and Acting President.

Scientific work Haddadin was a heterocyclic chemist whose contributions are marked by his co-invention, with Costas H. Issidorides, of a method of making hundreds if not thousands of heterocyclic compounds, in what is currently known in the chemical literature as “The Beirut Reaction”. Some of the compounds made by this method have antibacterial activities and anticancer properties. The latter are exemplified by the trade names of Carbadox and Mecadox which were marketed by the drug company: Chas. Pfizer. One compound TPZ (3-amino-1,2,4-benzotriazene 1,4-dioxide) is currently in the third stage of clinical testing as an anticancer drug. In addition, Haddadin has done original work in the areas of Isobenzofuran, Isoindoles, tetrazines, quinolines, furans, pyrroles, cinnolines and indazoles. He has ninety publications in refereed journals, and 42 patents in 25 countries. Haddadin co-discovered the Davis–Beirut chemical reaction with Mark Kurth and first published about it around 2005. In their seventh paper on the subject, Kurth and Haddadin named it after the universities where they worked, University of California, Davis and American University of Beirut. The paper has been cited 36 times in Google Scholar. Haddadin died on September 21, 2022.

References

Worked examples

Example 1 — a first encounter with Makhluf Haddadin

Start with the simplest possible case. Write down what Makhluf Haddadin claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Makhluf Haddadin before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Makhluf Haddadin ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Makhluf Haddadin

In research: Makhluf Haddadin appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Makhluf Haddadin in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Makhluf Haddadin is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1935 births, 2022 deaths, Academic staff of the American University of Beirut, so understanding it makes those chapters shorter.
In everyday life: Look for Makhluf Haddadin outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Makhluf Haddadin in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Makhluf Haddadin means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Makhluf Haddadin out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Makhluf Haddadin in simple terms?

Makhluf J. Haddadin (1935 – September 21, 2022) was a Jordanian chemistry professor at the American University of Beirut.

Why does Makhluf Haddadin matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Makhluf Haddadin?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Makhluf Haddadin.