Mammals normally have a pair of eyes. Although mammalian vision is not as excellent as bird vision, it is at least dichromatic for most of mammalian species, with certain families (such as Hominidae) possessing a trichromatic color perception. The dimensions of the eyeball vary only 1–2 mm among humans. The vertical axis is 24 mm, while the transverse is larger. At birth it is generally 16–17 mm, enlarging to 22.5–23 mm by three years of age. Between birth and age 13 the eye attains its mature size. It weighs 7.5 grams and its volume is roughly 6.5 ml. Along a line through the nodal (central) point of the eye is the optic axis, which is at a slight slant of five degrees toward the nose from the visual axis (i.e., the section going towards the focused point of the fovea).
Three layers The structure of the mammalian eye has a laminar organization that can be divided into three main layers or tunics whose names reflect their basic functions: the fibrous tunic, the vascular tunic, and the nervous tunic.
The fibrous tunic, also known as the tunica fibrosa oculi, is the outer layer of the eyeball consisting of the cornea and sclera. The sclera gives the eye most of its white color. It consists of dense connective tissue filled with the protein collagen to both protect the inner components of the eye and maintain its shape. The vascular tunic, also known as the tunica vasculosa oculi or the "uvea", is the middle vascularized layer which includes the iris, ciliary body, and choroid. The choroid contains blood vessels that supply the retinal cells with necessary oxygen and remove the waste products of respiration. The choroid gives the inner eye a dark color, which prevents disruptive reflections within the eye. The iris is seen rather than the cornea when looking straight in one's eye due to the latter's transparency, the pupil (central aperture of iris) is black because there is no light reflected out of the interior eye. If an ophthalmoscope is used, one can see the fundus, as well as vessels (which supply additional blood flow to the retina) especially those crossing the optic disk—the point where the optic nerve fibers depart from the eyeball—among others The nervous tunic, also known as the tunica nervosa oculi, is the inner sensory layer which includes the retina. Contributing to vision, the retina contains the photosensitive rod and cone cells and associated neurons. To maximise vision and light absorption, the retina is a relatively smooth (but curved) layer. It has two points at which it is different; the fovea and optic disc. The fovea is a dip in the retina directly opposite the lens, which is densely packed with cone cells. It is largely responsible for color vision in humans, and enables high acuity, such as is necessary in reading. The optic disc, sometimes referred to as the anatomical blind spot, is a point on the retina where the optic nerve pierces the retina to connect to the nerve cells on its inside. No photosensitive cells exist at this point, it is thus "blind". Continuous with the retina are the ciliary epithelium and the posterior epithelium of the iris. In addition to the rods and cones, a small proportion (about 1-2% in humans) of the ganglion cells in the retina are themselves photosensitive through the pigment melanopsin. They are generally most excitable by blue light, about 470–485 nm. Their information is sent to the SCN (suprachiasmatic nuclei), not to the visual center, through the retinohypothalamic tract which is formed as melanopsin-sensitive axons exit the optic nerve. It is primarily these light signals which regulate circadian rhythms in mammals and several other animals. Individuals with total blindness may not be able to transmit photoreceptor signals to the suprachiasmatic nucleus, and therefore may have desynchronized Circadian rhythms . The ipRGCs have other functions as well, such as signaling the need for changing the diameter of the pupil in changing light conditions.
Anterior and posterior segments
The mammalian eye can also be divided into two main segments: the anterior segment and the posterior segment. The human eye is not a plain sphere but is like two spheres combined, a smaller, more sharply curved one and a larger lesser curved sphere. The former, the anterior segment is the front sixth of the eye that includes the structures in front of the vitreous humour: the cornea, iris, ciliary body, and lens. Within the anterior segment are two fluid-filled spaces:
the anterior chamber between the posterior surface of the cornea (i.e. the corneal endothelium) and the iris. the posterior chamber between the iris and the front face of the vitreous. Aqueous humor fills these spaces within the anterior segment and provides nutrients to the surrounding structures. Some ophthalmologists specialize in the treatment and management of anterior segment disorders and diseases. The posterior segment is the back five-sixths of the eye that includes the anterior hyaloid membrane and all of the optical structures behind it: the vitreous humor, retina, choroid, and optic nerve. The radii of the anterior and posterior sections are 8 mm and 12 mm, respectively. The point of junction is called the limbus. On the other side of the lens is the second humour, the aqueous humour, which is bounded on all sides by the lens, the ciliary body, suspensory ligaments and by the retina. It lets light through without refraction, helps maintain the shape of the eye and suspends the delicate lens. In some animals, the retina contains a reflective layer (the tapetum lucidum) which increases the amount of light each photosensitive cell perceives, allowing the animal to see better under low light conditions. The tapetum lucidum, in animals that have it, can produce eyeshine, for example as seen in cat eyes at night. Red-eye effect, a reflection of red blood vessels, appears in the eyes of humans and other animals that have no tapetum lucidum, hence no eyeshine, and rarely in animals that have a tapetum lucidum. The red-eye effect is a photographic effect, not seen in nature. Some ophthalmologists specialise in this segment.
Extraocular anatomy Lying over the sclera and the interior of the eyelids is a transparent membrane called the conjunctiva. It helps lubricate the eye by producing mucus and tears. It also contributes to immune surveillance and helps to prevent the entrance of microbes into the eye.
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