The enzyme mannosyl-3-phosphoglycerate phosphatase (EC 3.1.3.70) catalyzes a chemical reaction which removes a phosphate group (Pi) by hydrolysis:
The enzyme was characterised in the thermophilic bacteria, Pyrococcus horikoshii, and the product 2-(α-D-mannosyl)-D-glyceric acid (mannosylglycerate) helps prevent osmotic shock. This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is 2-O-(α-D-mannosyl)-3-phosphoglycerate phosphohydrolase.
Structural studies As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB: 1WZC and PDB: 1XVI.
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