Membrane-spanning 4A genes are members of the CD20-like family. The MS4A genes are usually organized in a single genomic clusters in mammals, suggestive of gene duplication events. MS4A genes encode a class of four-transmembrane spanning proteins. MS4A genes have been described to act as a specific kind of olfactory receptor in the necklace olfactory sensory neurons in mice (Mus musculus). In human (Homo sapiens) the members of this family include:
MS4A1 (better known as "CD20") MS4A2 MS4A3 MS4A4A MS4A4E MS4A5 MS4A6A MS4A6E MS4A7 MS4A8 MS4A9 MS4A10 MS4A12 MS4A13 MS4A14 MS4A15 MS4A18
References