The Meningitis Vaccine Project is an effort to eliminate meningitis epidemics in Sub-Saharan Africa by developing a new meningococcal vaccine. Most outbreaks of meningococcal disease in the region, also known as the meningitis belt, are caused by serotype A of Neisseria meningitidis ("meningitis A"). In June 2010, various sources announced that they had developed MenAfriVac, which is an inexpensive, safe, and highly effective vaccine that reduces rates of meningitis A infection. The project marked the first time that medical research had developed a vaccine to combat a disease that is endemic to and only a problem for Africa. The project began in 2001 when the Bill & Melinda Gates Foundation awarded the World Health Organization and the Program for Appropriate Technology in Health (PATH) a US $70 million seed grant to begin research.
Background
In 2001, the Bill & Melinda Gates Foundation awarded the World Health Organization and the Program for Appropriate Technology in Health (PATH) a US$70 million seed grant to launch the Meningitis Vaccine Project.
Implementation The mission of the project is to eliminate meningococcal disease (colloquially referred to simply as meningitis) as a public health problem in sub-Saharan Africa through the development, testing, introduction, and widespread use of conjugate meningococcal vaccines. The project recently developed MenAfriVac, a low-cost conjugate A vaccine that is ready for widespread distribution to people between the ages of 1 and 29 in Burkina Faso, Mali, and Niger, three countries in the African meningitis belt with the highest rates of meningitis.
Manufacture By working with the Serum Institute of India Ltd. to manufacture the vaccine, the project was able to develop a vaccine that would be affordable to developing African countries, priced at less than $US.50 per dose. Unlike existing vaccines, MenAfriVac also provides immunity for a long period—10 to 15 years—and is safe for use in infants one year of age and older. Following successful trials, the vaccine was introduced in three African countries in 2010.
See also African meningitis belt 2009–10 West African meningitis outbreak Meningococcal vaccine
Sources
External links Official website PATH project page


