chemistry

Metaflumizone

Metaflumizone is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Metaflumizone rather than just read about it. In short: Metaflumizone is a semicarbazone broad-spectrum insecticide developed by Nihon Nohyaku with activity on Lepidoptera, Coleoptera, and certain Hemiptera. It is also used for the veterinary treatment of fleas and ticks, marketed under the brand name ProMeris.

Key takeaways

Metaflumizone belongs to chemistry; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Metaflumizone to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Metaflumizone from memory before moving on to harder problems.

Reference excerpt

Metaflumizone is a semicarbazone broad-spectrum insecticide developed by Nihon Nohyaku with activity on Lepidoptera, Coleoptera, and certain Hemiptera. It is also used for the veterinary treatment of fleas and ticks, marketed under the brand name ProMeris. A discontinued variant of ProMeris, called ProMeris Duo or Promeris for Dogs, was indicated for canine use and was a formulated blend of metaflumizone and amitraz. The metaflumizone-only formulation is waterproof and typically remain effective for 30–45 days in a cutaneous application at the base of the neck.

Similar insecticides Metaflumizone is chemically similar to pyrazoline sodium channel blocker insecticides (SCBIs) discovered at Philips-Duphar in the early 1970s, but is less dangerous to mammals than earlier compounds.

Action Metaflumizone belongs to IRAC group 22B and works by blocking sodium channels in target insects, resulting in flaccid paralysis. Metaflumizone blocks sodium channels by binding selectively to the slow-inactivated state, which is characteristic of the SCBIs. The toxin has been tested for efficacy against Spodoptera eridania moths and is indicated for control of fleas and ticks. However, in a cross comparison with other veterinary flea control substances, Metaflumizone was not shown to result in a significant reduction in the number of engorged adult female Culex mosquitoes. Therefore, its usefulness as a heartworm control treatment is likely to be insignificant when compared with comparable treatments such as selamectin that do impact the mosquito disease vector.

Adverse effects reported In 2011, Pfizer Animal Care decided to cease production of the drug based on findings which linked its use to an elevated incidence of the autoimmune disorder pemphigus foliaceus.

References

External links Metaflumizone in the Pesticide Properties DataBase (PPDB)

Illustrations

Worked examples

Example 1 — a first encounter with Metaflumizone

Start with the simplest possible case. Write down what Metaflumizone claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Metaflumizone before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Metaflumizone ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Metaflumizone

In research: Metaflumizone appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Metaflumizone in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Metaflumizone is common in secondary-school and first-year university syllabi. It links to neighbouring topics 4-(Trifluoromethyl)phenyl compounds, 4-Aminophenyl compounds, Benzonitriles, so understanding it makes those chapters shorter.
In everyday life: Look for Metaflumizone outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

Ask Teacher Smith questions about this articleOpens your AI tutor with a question about “Metaflumizone” →

Affiliate

Preply — study more efficiently by working with a personal tutor. 50% off.

How to study Metaflumizone in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Metaflumizone means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Metaflumizone out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Metaflumizone in simple terms?

Why does Metaflumizone matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Metaflumizone?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Metaflumizone.