engineering

Methanosarcina-phenazine hydrogenase

Methanosarcina-phenazine hydrogenase is a engineering topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Methanosarcina-phenazine hydrogenase rather than just read about it. In short: In enzymology, a Methanosarcina-phenazine hydrogenase (EC 1.12.98.3) is an enzyme that catalyzes the chemical reaction H2 + 2-(2,3-dihydropentaprenyloxy)phenazine ⇌ {\displaystyle \rightleftharpoons } 2-dihydropentaprenyloxyphenazine Thus, the two substrates of this enzyme are H2 and 2-(2,3-dihydropentaprenyloxy)phenazine, whereas its product is 2-dihydropentaprenyloxyphenazine. This enzyme belongs to the family of…

Key takeaways

Methanosarcina-phenazine hydrogenase belongs to engineering; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Methanosarcina-phenazine hydrogenase to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Methanosarcina-phenazine hydrogenase from memory before moving on to harder problems.

Reference excerpt

In enzymology, a Methanosarcina-phenazine hydrogenase (EC 1.12.98.3) is an enzyme that catalyzes the chemical reaction

H2 + 2-(2,3-dihydropentaprenyloxy)phenazine ⇌ {\displaystyle \rightleftharpoons } 2-dihydropentaprenyloxyphenazine Thus, the two substrates of this enzyme are H2 and 2-(2,3-dihydropentaprenyloxy)phenazine, whereas its product is 2-dihydropentaprenyloxyphenazine. This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with other, known, acceptors. The systematic name of this enzyme class is hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase. Other names in common use include methanophenazine hydrogenase, and methylviologen-reducing hydrogenase.

References

Abken HJ, Tietze M, Brodersen J, Baumer S, Beifuss U, Deppenmeier U (1998). "Isolation and characterization of methanophenazine and function of phenazines in membrane-bound electron transport of Methanosarcina mazei Go1". J. Bacteriol. 180 (8): 2027–32. doi:10.1128/JB.180.8.2027-2032.1998. PMC 107126. PMID 9555882. Deppenmeier U, Lienard T, Gottschalk G (1999). "Novel reactions involved in energy conservation by methanogenic archaea". FEBS Lett. 457 (3): 291–7. Bibcode:1999FEBSL.457..291D. doi:10.1016/S0014-5793(99)01026-1. PMID 10471795. Beifuss U, Tietze M, Baumer S, Deppenmeier U (2000). "Methanophenazine: Structure, Total Synthesis, and Function of a New Cofactor from Methanogenic Archaea This work was supported by the Deutsche Forschungsgemeinschaft (Sonderforschungsbereich 416; grants De 488/6-1 and De 488/4-2) and the Fonds der Chemischen Industrie We are grateful to Drs. J. Paust and H. Jaedicke (BASF AG, Ludwigshafen) and Dr. R. K. Muller (Hoffmann-La Roche Ltd., Basel) for generously providing chemicals". Angew. Chem. Int. Ed. Engl. 39 (14): 2470–2472. doi:10.1002/1521-3773(20000717)39:14<2470::AID-ANIE2470>3.0.CO;2-R. PMID 10941105.

Worked examples

Example 1 — a first encounter with Methanosarcina-phenazine hydrogenase

Start with the simplest possible case. Write down what Methanosarcina-phenazine hydrogenase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In engineering, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Methanosarcina-phenazine hydrogenase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Methanosarcina-phenazine hydrogenase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Methanosarcina-phenazine hydrogenase

In research: Methanosarcina-phenazine hydrogenase appears in engineering research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Methanosarcina-phenazine hydrogenase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Methanosarcina-phenazine hydrogenase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 1.12.98, Enzymes of unknown structure, Oxidoreductase stubs, so understanding it makes those chapters shorter.
In everyday life: Look for Methanosarcina-phenazine hydrogenase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Methanosarcina-phenazine hydrogenase in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Methanosarcina-phenazine hydrogenase means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Methanosarcina-phenazine hydrogenase out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Methanosarcina-phenazine hydrogenase in simple terms?

In enzymology, a Methanosarcina-phenazine hydrogenase (EC 1.12.98.3) is an enzyme that catalyzes the chemical reaction H2 + 2-(2,3-dihydropentaprenyloxy)phenazine ⇌ {\displaystyle \rightleftharpoons } 2-dihydropentaprenyloxyphenazine Thus, the two substrates of this enzyme are H2 and 2-(2,3-dihydro…

Why does Methanosarcina-phenazine hydrogenase matter?

Because it connects several engineering ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Methanosarcina-phenazine hydrogenase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Methanosarcina-phenazine hydrogenase.