Metharbital was patented in 1905 by Emil Fischer working for Merck. It was marketed as Gemonil by Abbott Laboratories. It is a barbiturate anticonvulsant, used in the treatment of epilepsy. It has similar properties to phenobarbital.
History 1952 Gemonil was introduced by Abbott Laboratories. 1990 Abbott stopped marketing.
Synthesis Metharbital can be synthesized from 2,2-diethylmalonic acid and O-methylisourea.
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