Methylpiperidinopyrazole (MPP) is a synthetic, nonsteroidal, and highly selective antagonist of ERα that is used in scientific research to study the function of this receptor. It has 200-fold selectivity for ERα over ERβ and 1000-fold selectivity for blocking ERα-mediated gene transcription relative to that of ERβ.
See also Glyceollin Propylpyrazoletriol (PPT) Diarylpropionitrile (DPN) Prinaberel (ERB-041) Liquiritigenin Menerba PHTPP (R,R)-Tetrahydrochrysene ((R,R)-THC)
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