In molecular biology, miR395 is a conserved plant microRNA that regulates genes involved in sulfur metabolism and transport. Like other plant microRNAs, miR395 controls gene expression by directing cleavage or translational repression of target mRNAs. miR395 was initially identified computationally in plants including Arabidopsis thaliana and Oryza sativa. Members of the miR395 family primarily target transcripts encoding ATP sulfurylase enzymes and sulfate transporters, key components of sulfate assimilation pathways. In Arabidopsis, expression of miR395 is strongly induced under sulfate-limiting conditions. The mature miRNA then regulates sulfate uptake and allocation by targeting ATP sulfurylase genes and the sulfate transporter SULTR2;1, helping coordinate sulfur homeostasis in plants.
See also MicroRNA
References
External links
Page for mir-395 microRNA precursor family at Rfam miRBase


