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Microdispensing

Microdispensing is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Microdispensing rather than just read about it. In short: Microdispensing is the technique of producing liquid media dosages in volumes of less than one microlitre. The continuing miniaturization in almost all technical areas creates constant challenges for industry, development and research facilities.

Key takeaways

  • Microdispensing belongs to science; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Microdispensing to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Microdispensing from memory before moving on to harder problems.

Reference excerpt

Microdispensing is the technique of producing liquid media dosages in volumes of less than one microlitre. The continuing miniaturization in almost all technical areas creates constant challenges for industry, development and research facilities. Microdispensing is one of those challenges. Ever smaller amounts of adhesive, liquid, oil, grease and a multitude of other media must be dispensed reliably and accurately in dosage and placement with short cycle times. The precise positioning and quantity of fluids such as glue, reagents or any other substance has a great influence on the overall quality of a medical device. A few examples are:

Micro-dosing systems with a quantity as small as 50 picolitres Volumetric systems for use with adhesives and spraying systems for silicone coating needles and other surfaces Microdispensing is also used in non-medical applications, like on-demand soda flavoring (the Coca-Cola Freestyle and Pepsi Spire), inkjet printing, and 3-D printing.

Dispensing techniques There are two basic types of dispensing techniques: classic contact dispensing and non-contact dispensing.

Contact dispensing In contact dispensing, the drop forms at the exit of a nozzle, and is deposited by contact, while the drop is still on the nozzle. The technique is as old as the wish to divide a medium, stored in a big container, into smaller amounts. A good example for this is applying adhesive with a tube: To apply the adhesive requires contact between the tip of the tube and the part for the bead of adhesive to be transferred. This method has disadvantages:

Slow dispensing Part has to be touched Part could be damaged Adhesive forms threads Adhesive is not in the expected place Adhesive amounts are difficult to reproduce Despite all of these disadvantages, contact dispensing is still used in the majority of automated processes today, because of:

A lack of knowledge regarding non-contact dispensing systems Few manufacturers for non-contact dispensing systems No direct access to dispensing area (e.g. undercuts) Medium can not be dispensed without contact Dispensing without stress to Medium is possible More precise dispensing especially at bead dispensing Simple to clean in most cases

Typical technologies for contact dispensing Gear pump

high-frequency pulsation high performance always valves no solids possible Pressure-time systems

many components pragmatic evaluation of quantity and control add. power source: air volume flow depends on pressure, time and temperature

Non-contact dispensing (Jetting) In non-contact dispensing, the drop also forms at the end of a nozzle, but far enough away from the target area that the drop separates from the nozzle before it hits. This, too, is a very old technique, as old as squirting liquid from a tube. Because of increasing requirements in regards to cycle time and accuracy in almost all areas of production, non-contact dispensing is constantly gaining importance. A good example for this is the attachment of very small electronic parts (SMD parts) onto printed circuit boards and substrates. For this, the part carrier only needs to be positioned in one plane - after that the adhesive can be transferred without contact. The following examples show the advantages of non-contact dispensing:

Removal of a feed motion to the part Time saving through ejection of adhesive No contact with part (no damage) Even spread of adhesive topography independent of part topography and surface structure Non-contact dispensing can be divided in two different methods:

Jet-forming dispensing Dynamic drop dispensing

Jet-forming dispensing Jet-forming dispensing exists when the flow velocity of a medium at the nozzle exit is high enough that the effects of gravitation and surface tension on the separation of the fluid from the nozzle are of secondary importance. This state is characterized by the Weber number:

W e = ρ v 2 D σ {\displaystyle \mathrm {We} ={\frac {\rho v^{2}D}{\sigma }}}

where

The physical border line between drop- and jet-forming is around a Weber-number of 8. At this point the dynamic pressure of the flowing medium exceeds the pressure from the surface tension of the drop, which therefore sticks to the nozzle. This transitional stage can be demonstrated at a water tap by gradually increasing the flow, going from the dropping status until a continuous water jet has formed. The Weber-number in this case is, however, clearly above 8, because of the jet exit conditions of the nozzle. By using the Weber-number, the theoretical lower limit of the mass flow can be found for the jet-forming conditions. In actual applications, to assure a safe dispensing process, the real Weber-numbers chosen should be between 20 and 50. For a calculated estimation of the fluid flow velocity in the nozzle, for fluids with Newtonian flow behavior, the formula for capillary fluid flow according to the Hagen–Poiseuille law has been proven.

Q = Δ P π r 4 8 μ L {\displaystyle Q={\frac {\Delta P\pi r^{4}}{8\mu L}}}

To avoid atomizing of the fluid at the nozzle exit, the fluid flow in the nozzle must be laminar, which is the case as long as the Reynolds number (Re) of the nozzle is smaller than the critical Reynolds-number of the nozzle:

R e < R e c r i t {\displaystyle Re<Re_{crit}}

Reynolds-number of the nozzle:

R e = ρ v D μ {\displaystyle Re={\frac {\rho vD}{\mu }}}

Critical Reynolds-number of the nozzle:

… excerpt ends here. Continue reading the full article.

Worked examples

Example 1 — a first encounter with Microdispensing

Start with the simplest possible case. Write down what Microdispensing claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Microdispensing before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Microdispensing ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Microdispensing

In research
Microdispensing appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Microdispensing in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Microdispensing is common in secondary-school and first-year university syllabi. It links to neighbouring topics Drug delivery devices, Industrial processes, Routes of administration, so understanding it makes those chapters shorter.
In everyday life
Look for Microdispensing outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Microdispensing in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Microdispensing means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Microdispensing out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Microdispensing in simple terms?

Microdispensing is the technique of producing liquid media dosages in volumes of less than one microlitre. The continuing miniaturization in almost all technical areas creates constant challenges for industry, development and research facilities.

Why does Microdispensing matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Microdispensing?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Microdispensing.

Tags

  • Drug delivery devices
  • Industrial processes
  • Routes of administration

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