Motexafin lutetium is a texaphyrin, developed by Pharmacyclics Inc. (proposed trade names Lutrin, Antrin and Optrin) It is a photosensitiser for use in photodynamic therapy to treat skin conditions and superficial cancers. It has also been tested for use in photoangioplasty (photodynamic treatment of diseased arteries). It is photoactivated by 732 nm light which allows greater depth of penetration.
Clinical trials Phase II clinical trials were in progress in 1999. A phase I trial for prostate cancer reported in 2009. As of 2017, this drug is no longer being developed.
See also Motexafin gadolinium
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