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Multi-Omics Profiling Expression Database

Multi-Omics Profiling Expression Database is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Multi-Omics Profiling Expression Database rather than just read about it. In short: The Multi-Omics Profiling Expression Database (MOPED) was an expanding multi-omics resource that supports rapid browsing of transcriptomics and proteomics information from publicly available studies on model organisms and humans. As to date (2021) it has ceased activities and is unaccessible online.

Key takeaways

  • Multi-Omics Profiling Expression Database belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Multi-Omics Profiling Expression Database to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Multi-Omics Profiling Expression Database from memory before moving on to harder problems.

Reference excerpt

The Multi-Omics Profiling Expression Database (MOPED) was an expanding multi-omics resource that supports rapid browsing of transcriptomics and proteomics information from publicly available studies on model organisms and humans. As to date (2021) it has ceased activities and is unaccessible online.

Systematic Protein Investigative Research Environment MOPED is designed to simplify the comparison and sharing of data for the greater research community. MOPED employs the standardized analysis pipeline SPIRE to uniquely provide protein level absolute and relative expression data, meta- analysis capabilities and quantitative data. Processed relative expression transcriptomics data were obtained from the Gene Expression Omnibus (GEO). Data can be queried for specific proteins and genes, browsed based on organism, tissue, localization and condition, and sorted by false discovery rate and expression. MOPED empowers users to visualize their own expression data and compare it with existing studies. Further, MOPED links to various protein and pathway data- bases, including GeneCards, Panther, Entrez, UniProt, KEGG, SEED, and Reactome. Protein and gene identifiers are integrated from GeneCards (cross-referenced with MOPED), Genbank, RefSeq, UniProt, WormBase, and Saccharomyces Genome Database (SGD). The current version of MOPED (MOPED 2.5, 2014) contains approximately 5 million total records including ~260 experiments and ~390 conditions. MOPED is developed and supported by the Kolker team at Seattle Children's Research Institute.

Model Organism Protein Expression Database MOPED was previously known as the Model Organism Protein Expression Database, before changing its name to the Multi-Omics Profiling Expression Database.

References

Further reading

Worked examples

Example 1 — a first encounter with Multi-Omics Profiling Expression Database

Start with the simplest possible case. Write down what Multi-Omics Profiling Expression Database claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Multi-Omics Profiling Expression Database before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Multi-Omics Profiling Expression Database ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Multi-Omics Profiling Expression Database

In research
Multi-Omics Profiling Expression Database appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Multi-Omics Profiling Expression Database in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Multi-Omics Profiling Expression Database is common in secondary-school and first-year university syllabi. It links to neighbouring topics Biological databases, Omics, Proteomics, so understanding it makes those chapters shorter.
In everyday life
Look for Multi-Omics Profiling Expression Database outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Multi-Omics Profiling Expression Database in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Multi-Omics Profiling Expression Database means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Multi-Omics Profiling Expression Database out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Multi-Omics Profiling Expression Database in simple terms?

The Multi-Omics Profiling Expression Database (MOPED) was an expanding multi-omics resource that supports rapid browsing of transcriptomics and proteomics information from publicly available studies on model organisms and humans. As to date (2021) it has ceased activities and is unaccessible online.

Why does Multi-Omics Profiling Expression Database matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Multi-Omics Profiling Expression Database?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Multi-Omics Profiling Expression Database.

Tags

  • Biological databases
  • Omics
  • Proteomics

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