N-Phosphonooxymethyl-DMT, or N-POM-DMT, also known as VLS-02-23-10, is a psychedelic drug of the tryptamine family related to dimethyltryptamine (DMT). It is the N-phosphonooxymethyl derivative of DMT. The drug is a prodrug of DMT with modified pharmacokinetic properties compared to DMT in rodents. The chemical synthesis of N-phosphonooxymethyl-DMT has been described. Various analogues of N-phosphonooxymethyl-DMT have also been described. One of these is N-phosphonooxymethyl-5-MeO-DMT (N-POM-5-MeO-DMT), which is a putative prodrug of 5-MeO-DMT. N-Phosphonooxymethyl-DMT was patented by Tanweer A. Khan and colleagues in affiliation with Atai Therapeutics in 2024.
See also Substituted tryptamine N-(2-Cyanoethyl)tryptamine (CE-T) 1-Benzoyl-DMT (1Bz-DMT) 1-Acetyl-5-MeO-DMT (1A-5-MeO-DMT) NBoc-DMT (N′-tert-butoxycarbonyl-DMT)
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