N-hydroxythioamide S-beta-glucosyltransferase (EC 2.4.1.195) is an enzyme that catalyzes several chemical reactions that are part of the biosynthesis of plant glucosinolates. For example, 4-methylthiobutylthiohydroximate is converted to 3-methylthiopropyl-desulfoglucosinolate by transfer of a glucose unit from UDP-glucose, giving uridine diphosphate (UDP) as a byproduct:
The enzyme has been characterised from Brassica napus and Arabidopsis. It belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:N-hydroxy-2-phenylethanethioamide S-beta-D-glucosyltransferase. Other names in common use include desulfoglucosinolate-uridine diphosphate glucosyltransferase, uridine diphosphoglucose-thiohydroximate glucosyltransferase, thiohydroximate beta-D-glucosyltransferase, UDPG:thiohydroximate glucosyltransferase, thiohydroximate S-glucosyltransferase, thiohydroximate glucosyltransferase, and UDP-glucose:thiohydroximate S-beta-D-glucosyltransferase.
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