NADH:ubiquinone oxidoreductase complex assembly factor 8 is a protein that in humans is encoded by the NDUFAF8 gene. This protein stabilizes NDUFAF5 during assembly of mitochondrial Complex I.
Structure The NDUFAF8 gene is located on the q arm of chromosome 17 in position 25.3 and spans 1,987 base pairs. The gene produces a 7.756 kDa protein composed of 74 amino acids.
Function The protein encoded by the NDUFAF8 gene is involved in the assembly of mitochondrial Complex I (NADH-ubiquinone oxidoreductase). This protein is required to stabilize NDUFAF5 during assembly of Complex I.
Interaction NDUFAF8 has protein-protein interactions with NDUFAF5, stabilizing it.
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Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.



