chemistry

Nabil Seidah

Nabil Seidah is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Nabil Seidah rather than just read about it. In short: Nabil G. Seidah, (born 1949) is a Canadian Québécois scientist.

Key takeaways

Nabil Seidah belongs to chemistry; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Nabil Seidah to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Nabil Seidah from memory before moving on to harder problems.

Reference excerpt

Nabil G. Seidah, (born 1949) is a Canadian Québécois scientist. Born in Egypt, he was educated at Cairo University, and subsequently at Georgetown University where he obtained his Ph.D. in 1973. He emigrated to Canada and has been working at the Clinical Research Institute of Montreal (IRCM) since 1974. He is the director of the laboratory of Biochemical Neuroendocrinology. He discovered and cloned seven (PC1, PC2, PC4, PC5, PC7, SKI-1 and PCSK9) of the nine known enzymes belonging to the convertase family. During this period, he also greatly contributed to demonstrating that the proteolysis by the proprotein convertases is a wide mechanism that also concerns “non-neuropeptide” proteins such as growth factors, α-integrins, receptors, enzymes, membrane-bound transcription factors, and bacterial and viral proteins. In 2003, he discovered PCSK9 and showed that point mutations in the PCSK9 gene cause dominant familial hypercholesterolemia, likely because of a gain of function related to the ability of PCSK9 to enhance the degradation of cell surface receptors, such as the low-density lipoprotein receptor (LDLR). He has since worked on the elucidation of the functions and mechanisms of action of PCSK9 and PCSK7 both in cells and in vivo, and is developing specific PCSK9 and PCSK7 inhibitors/silencers.

Awards 1977 - The Clarke Institute of Psychiatry Award 1983 - Marcel-Piché Prize 1991 - Made Fellow of the Royal Society of Canada 1994 - Manning Award of Distinction 1995 - Medical Research Council Distinguished Scientist Award 1997 - Made Officer of the Ordre national du Québec 1999 - Made member of the Order of Canada 1999 - Medal of Honor, Pharmaceutical Manufacturers Association of Canada (PMAC) Health Research Foundation 2001 - Winner of the McLaughlin medal 2001 - Winner of the Léo-Pariseau Prize 2003-2024 - Canada Chair Tier 1 in Precursor Proteolysis 2009 - Pfizer Distinguished Cardiovascular-Metabolic Research Jean-Davignon Award 2011 - Wilder-Penfield Prize in Biomedical Research in Québec 2013 - Queen Elizabeth II Diamond Jubilee Medal 2013 - Simon Pierre-Noël Memorial Lecture Award in Lipid Research 2014 - Jacques Genest Award from the Canadian Society of Endocrinology & Metabolism 2015 - Anne and Neil McArthur Research Award 2016 - CIHR Distinguished Lecturer Award in Cardiovascular Sciences 2018 - Grand Prix scientifique de la Fondation Lefoulon-Delalande 2018 - Akira Endo Award 2018 - Lucian Award 2021 - Elected member of the Canadian Academy of Health Sciences [CAHS]

References

Worked examples

Example 1 — a first encounter with Nabil Seidah

Start with the simplest possible case. Write down what Nabil Seidah claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Nabil Seidah before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Nabil Seidah ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Nabil Seidah

In research: Nabil Seidah appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Nabil Seidah in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Nabil Seidah is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1949 births, 20th-century Canadian scientists, 21st-century Canadian scientists, so understanding it makes those chapters shorter.
In everyday life: Look for Nabil Seidah outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

Ask Teacher Smith questions about this articleOpens your AI tutor with a question about “Nabil Seidah” →

Affiliate

Preply — study more efficiently by working with a personal tutor. 50% off.

How to study Nabil Seidah in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Nabil Seidah means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Nabil Seidah out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Nabil Seidah in simple terms?

Nabil G. Seidah, (born 1949) is a Canadian Québécois scientist.

Why does Nabil Seidah matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Nabil Seidah?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Nabil Seidah.