Naringenin 8-dimethylallyltransferase (EC 2.5.1.70) is an enzyme characterised from Sophora flavescens that catalyzes a chemical reaction that converts naringenin to its 8-prenyl derivative by adding the 5-carbon unit from dimethylallyl pyrophosphate. This gives 8-prenylnaringenin (also called sophoraflavanone B), with pyrophosphate (PPi) as a byproduct:
This enzyme is a transferase, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is dimethylallyl-diphosphate:naringenin 8-dimethylallyltransferase. It is also called N8DT and is part of the biosynthesis pathway to sophoraflavanone G.
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