The National Microbiology Laboratory (NML) is part of the Public Health Agency of Canada (PHAC), the agency of the Government of Canada that is responsible for public health, health emergency preparedness and response, and infectious and chronic disease control and prevention. NML is located in several sites across the country including the Canadian Science Centre for Human and Animal Health (CSCHAH) in Winnipeg, Manitoba. NML has a second site in Winnipeg, the JC Wilt Infectious Disease Research Centre on Logan Avenue which serves as a hub for HIV research and diagnostics in Canada. The three other primary sites include locations in Guelph, St. Hyacinthe and Lethbridge. The CSCHAH is a biosafety level 4 infectious disease laboratory facility, the only one of its kind in Canada. With maximum containment, scientists are able to work with pathogens including Ebola, Marburg and Lassa fever. The NML's CSCHAH is also home to the Canadian Food Inspection Agency's National Centre for Foreign Animal Disease, and thus the scientists at the NML share their premises with animal virologists.
History The National Microbiology Laboratory was preceded by the Bureau of Microbiology which was originally part of the Laboratory Centre for Disease Control of Health Canada in Ottawa. In the 1980s, Health Canada identified both the need to replace existing laboratory space that was reaching the end of its lifespan and the need for Containment Level 4 space in the country. Around the same time, Agriculture Canada (prior to the Canadian Food Inspection Agency being formed) also identified the need for new laboratory space including high-containment. Numerous benefits were identified for housing both laboratories in one building and Winnipeg was chosen as the site; an announcement to that effect was made in October 1987. After some debate, the spot chosen for the site was a city works yard near to the Health Sciences Centre (a major teaching hospital), the University of Manitoba's medical school, and other life science organizations. Construction of the facility that came to be named the Canadian Science Centre for Human and Animal Health (often referred to locally as "the Virology Lab") began with an official ground-breaking in December 1992. The joint venture design team of Toronto-based Dunlop Architects and Winnipeg-based Smith Carter Architects and Engineers visited 30 laboratories to seek best practices in containment and design. Construction was largely complete by the end of 1997 with the first programs beginning in the spring of 1998 and all laboratories coming on line after that. The official opening took place in June 1999. Following the SARS outbreak in 2003, the Public Health Agency of Canada was formed in 2004 to provide a stronger focus on public health and emergency preparedness in the country. It is a member of the federal Health Portfolio (along with Health Canada, the Canadian Institute of Health Research, and other organizations). By 2018 the NML was beginning to use genomics and advanced computing to study microbes at the genetic level in so-called "dry lab" facilities, as opposed to "wet labs" with Petri dishes and cell cultures. The NML (PHAC) fired Chinese nationals Xiangguo Qiu and her husband Keding Cheng from their jobs as BSL4 infectious disease researchers in January 2021; previously in July 2019 the pair had been dismissed from their positions as unpaid members of the University of Winnipeg for their agency in a mysterious trans-Pacific shipment of BSL4-grade virus materials back to their homeland when the RCMP was called in.
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