Neuronal Calcium Sensor is a large family of proteins which work as calcium dependent molecular switches and includes members like Frequenin (NCS1), recoverin, GCAP, neurocalcin, visinin etc. All the members carry 4 EF hand motifs (out of which only 2 or 3 bind calcium) and an N-myristoyl group.
Members of NCS family Highly evolutionarily conserved NCS1 (Frequenin) VILIP-1 (Visinin-like-protein-1) HPCAL4 (Visinin-like-protein-2) HPCAL1 (Visinin-like-protein-3) hippocalcin neurocalcin recoverin Guanylate cyclase activator proteins (GCAPs) Potassium Channel interacting proteins (KChIPs 1–4), including: KCNIP1, KCNIP2, Calsenilin or DREAM/KChIP-3/KCNIP3 (downstream regulatory element antagonist modulator/potassium channel interacting protein), KCNIP4
References
External links Neuronal+Calcium-Sensor+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH) NCS proteins
