The neuroscience of music is the scientific study of brain-based mechanisms involved in the cognitive processes underlying music. These behaviours include music listening, perceiving, performing, composing, reading, writing, and other related activities. It also is increasingly concerned with the brain basis for musical aesthetics and musical emotion. Scientists working in this field may have training in cognitive neuroscience, neurology, neuroanatomy, psychology, music theory, computer science, and other relevant fields. The cognitive neuroscience of music represents a significant branch of music psychology, and is distinguished from related fields such as cognitive musicology in its reliance on direct observations of the brain and use of brain imaging techniques like functional magnetic resonance imaging (fMRI) and positron emission tomography (PET).
Elements of music
Pitch
Sounds consist of waves of air molecules that vibrate at different frequencies. These waves travel to the basilar membrane in the cochlea of the inner ear. Different frequencies of sound will cause vibrations in different locations of the basilar membrane. We are able to hear different pitches because each sound wave with a unique frequency is correlated to a different location along the basilar membrane. This spatial arrangement of sounds and their respective frequencies being processed in the basilar membrane is known as tonotopy. When the hair cells on the basilar membrane move back and forth due to the vibrating sound waves, they release neurotransmitters and cause action potentials to occur down the auditory nerve. The auditory nerve then leads to several layers of synapses at numerous clusters of neurons, or nuclei, in the auditory brainstem. These nuclei are also tonotopically organized, and the process of achieving this tonotopy after the cochlea is not yet well understood. This tonotopy is in general maintained up to primary auditory cortex in mammals. A widely postulated mechanism for pitch processing in the early central auditory system is the phase-locking and mode-locking of action potentials to frequencies in a stimulus. Phase-locking to stimulus frequencies has been shown in the auditory nerve, the cochlear nucleus, the inferior colliculus, and the auditory thalamus. By phase- and mode-locking in this way, the auditory brainstem is known to preserve a good deal of the temporal and low-passed frequency information from the original sound; this is evident by measuring the auditory brainstem response using EEG. This temporal preservation is one way to argue directly for the temporal theory of pitch perception, and to argue indirectly against the place theory of pitch perception.
The right secondary auditory cortex has finer pitch resolution than the left. Hyde, Peretz and Zatorre (2008) used functional magnetic resonance imaging (fMRI) in their study to test the involvement of right and left auditory cortical regions in the frequency processing of melodic sequences. As well as finding superior pitch resolution in the right secondary auditory cortex, specific areas found to be involved were the planum temporale (PT) in the secondary auditory cortex, and the primary auditory cortex in the medial section of Heschl's gyrus (HG). Many neuroimaging studies have found evidence of the importance of right secondary auditory regions in aspects of musical pitch processing, such as melody. Many of these studies such as one by Patterson, Uppenkamp, Johnsrude and Griffiths (2002) also find evidence of a hierarchy of pitch processing. Patterson et al. (2002) used spectrally matched sounds which produced: no pitch, fixed pitch or melody in an fMRI study and found that all conditions activated HG and PT. Sounds with pitch activated more of these regions than sounds without. When a melody was produced activation spread to the superior temporal gyrus (STG) and planum polare (PP). These results support the existence of a pitch processing hierarchy.
Absolute pitch
Absolute pitch (AP) is defined as the ability to identify the pitch of a musical tone or to produce a musical tone at a given pitch without the use of an external reference pitch. Neuroscientific research has not discovered a distinct activation pattern common for possessors of AP. Zatorre, Perry, Beckett, Westbury and Evans (1998) examined the neural foundations of AP using functional and structural brain imaging techniques. Positron emission tomography (PET) was utilized to measure cerebral blood flow (CBF) in musicians possessing AP and musicians lacking AP. When presented with musical tones, similar patterns of increased CBF in auditory cortical areas emerged in both groups. AP possessors and non-AP subjects demonstrated similar patterns of left dorsolateral frontal activity when they performed relative pitch judgments. However, in non-AP subjects activation in the right inferior frontal cortex was present whereas AP possessors showed no such activity. This finding suggests that musicians with AP do not need access to working memory devices for such tasks. These findings imply that there is no specific regional activation pattern unique to AP. Rather, the availability of specific processing mechanisms and task demands determine the recruited neural areas.
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