science

New York Genome Center

New York Genome Center is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand New York Genome Center rather than just read about it. In short: The New York Genome Center (NYGC) is an independent 501(c)(3) nonprofit academic research institution in New York City. It serves as a multi-institutional collaborative hub focused on the advancement of genomic science and its application to drive novel biomedical discoveries.

Key takeaways

New York Genome Center belongs to science; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect New York Genome Center to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of New York Genome Center from memory before moving on to harder problems.

Reference excerpt

The New York Genome Center (NYGC) is an independent 501(c)(3) nonprofit academic research institution in New York City. It serves as a multi-institutional collaborative hub focused on the advancement of genomic science and its application to drive novel biomedical discoveries. NYGC's areas of focus include the development of computational and experimental genomic methods and disease-focused research to better understand the genetic basis of cancer, neurodegenerative disease, and neuropsychiatric disease. In 2020, NYGC also has directed its expertise to COVID-19 genomics research.

Purpose and organization The Center leverages strengths in whole genome sequencing, genomic analysis, and development of genomic tools to advance genomic discovery. Its faculty hold joint tenure-track appointments at its member institutions and lead independent research labs at the center. NYGC's scientists bring a multidisciplinary and in-depth approach to the field of genomics, conducting research in single cell genomics, gene engineering, population and evolutionary genomics, technology and methods development, statistics, computational biology and bioengineering. In 2017, co-founder Tom Maniatis was named Evnin Family Scientific Director and chief executive officer of the New York Genome Center.

Founding The center was founded in November 2011 as a collaboration among eleven academic institutions to advance genome research, based on the vision of Dietrich A. Stephan and leadership from Tom Maniatis and financial support of $2.5 million from each institution as well as from visionary private philanthropists. In November 2012, the center recruited Robert B. Darnell as president and Scientific Director, where he served as CEO and Founding Director, before returning to Rockefeller University and Howard Hughes Medical Institute Investigator in 2017. NYGC formally opened in a multi-story building at 101 Avenue of the Americas. on September 19–20, 2013. The 12 founding institutions (Albert Einstein College of Medicine joined the original 11 institutions in April 2013) were:

Cold Spring Harbor Laboratory (New York) Columbia University (New York) Weill Cornell Medicine (New York) Memorial Sloan Kettering Cancer Center (New York) Icahn School of Medicine at Mount Sinai (New York) New York—Presbyterian Hospital (New York) New York University (New York) Northwell Health (New York) The Jackson Laboratory (Maine) Rockefeller University (New York) Stony Brook University (New York) Albert Einstein College of Medicine (New York) Currently, NYGC has 20 member institutions with Hackensack Meridian Health and Georgetown Lombardi Comprehensive Cancer Center joining in December 2019 as associate members. and Rutgers Cancer Institute of New Jersey joining as associate member in 2020.

Funding The New York Genome Center is a 501(c)(3) nonprofit academic research institution in New York City. Since its inception, the center has raised over $500 million to support its genomic research, including federal and private grants and philanthropy. This includes two joint gifts from the Simons Foundation and the Carson Family Charitable Trust; $100 million in 2016 and $125 million in 2019. The New York Genome Center also receives support from its member institutions, as well as New York State, the Empire State Development Corporation, the Partnership Fund for New York City, and the New York City Economic Development Corporation. Government funding has included a $55 million grant from New York State to support genomic medicine. In 2016 it received a $40 million grant from the National Human Genome Research Institute to establish a Center for Common Disease Genomics, and is leading a collaborative, large-scale genomic sequencing program focused on advancing understanding of common diseases, including autism. Additionally, the Center and Weill Cornell Medicine received a National Cancer Institute grant to support a joint cancer genomics data center for the research and clinical interpretation of tumors, a part of the ongoing development of The Cancer Genome Atlas. The center was also awarded a $13.5 million contract in 2015 to conduct whole genome sequencing and analysis for the National Heart, Lung, and Blood Institute's TOPMed program. In 2017, New York State committed $17 million in capital improvements for the New York Genome Center to house JLABS@NYC, a life sciences incubator, which opened in summer 2018.

Notable faculty Harold E. Varmus, MD | Senior Associate Core Member Michael Wigler, PhD | Senior Associate Core Member Simon Tavaré, PhD | Senior Associate Core Member

Recent Publications In the last five years, NYGC scientists have published over 200 papers in leading scientific journals. For an up-to-date listing of publications, go to https://www.nygenome.org/lab-groups-overview/publications/ Archived 26 January 2019 at the Wayback Machine

Notes

References

Illustrations

Worked examples

Example 1 — a first encounter with New York Genome Center

Start with the simplest possible case. Write down what New York Genome Center claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to New York Genome Center before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about New York Genome Center ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of New York Genome Center

In research: New York Genome Center appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses New York Genome Center in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: New York Genome Center is common in secondary-school and first-year university syllabi. It links to neighbouring topics 2011 establishments in New York City, Bioinformatics organizations, DNA sequencing, so understanding it makes those chapters shorter.
In everyday life: Look for New York Genome Center outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study New York Genome Center in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what New York Genome Center means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain New York Genome Center out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is New York Genome Center in simple terms?

Why does New York Genome Center matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study New York Genome Center?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on New York Genome Center.