computer science

Nextbio

Nextbio is a computer science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Nextbio rather than just read about it. In short: NextBio is a privately owned software company that provides a platform for drug companies and life science researchers to search, discover, and share knowledge across public and proprietary data. It was co-founded by Saeid Akhtari, Ilya Kupershmidt, and Mostafa Ronaghi in 2004, and based in Cupertino, California, United States.

Key takeaways

Nextbio belongs to computer science; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Nextbio to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Nextbio from memory before moving on to harder problems.

Reference excerpt

NextBio is a privately owned software company that provides a platform for drug companies and life science researchers to search, discover, and share knowledge across public and proprietary data. It was co-founded by Saeid Akhtari, Ilya Kupershmidt, and Mostafa Ronaghi in 2004, and based in Cupertino, California, United States. The NextBio Platform is an ontology-based semantic framework that connects highly heterogeneous data and textual information. The semantic framework is based on gene, tissue, disease, and compound ontologies. This framework contains information from different organisms, platforms, data types. and research areas that is integrated into and correlated within a single searchable environment using proprietary algorithms. It provides a unified interface for researchers to formulate and test new hypotheses across vast collections of experimental data. According to the company, the enterprise version of the NextBio platform is being used in life science research and development and drug development by researchers and clinicians at: Merck Pharmaceutical, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Celgene, Genzyme, Eli Lilly and Company, and Regeneron Pharmaceuticals. This enterprise version allows internal, proprietary data to be uploaded and integrated into the NextBio database of publicly available data. According to the company, scientists are using NextBio to improve their ability to identify relevant prognostic and predictive molecular signatures which are significant in their research. In October 2013, Illumina acquired NextBio. In 2015, the NextBio research platform was rebranded as Correlation Engine.

References

Worked examples

Example 1 — a first encounter with Nextbio

Start with the simplest possible case. Write down what Nextbio claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In computer science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Nextbio before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Nextbio ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Nextbio

In research: Nextbio appears in computer science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Nextbio in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Nextbio is common in secondary-school and first-year university syllabi. It links to neighbouring topics Bioinformatics companies, Health care companies based in California, Health care companies established in 2004, so understanding it makes those chapters shorter.
In everyday life: Look for Nextbio outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Nextbio in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Nextbio means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Nextbio out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Nextbio in simple terms?

Why does Nextbio matter?

Because it connects several computer science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Nextbio?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Nextbio.