engineering

Nickel-transporting ATPase

Nickel-transporting ATPase is a engineering topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Nickel-transporting ATPase rather than just read about it. In short: In enzymology, a nickel-transporting ATPase (EC 3.6.3.24) is an enzyme that catalyzes the chemical reaction ATP + H2O + Ni2+out ⇌ {\displaystyle \rightleftharpoons } ADP + phosphate + Ni2+in The 3 substrates of this enzyme are ATP, H2O, and Ni2+, whereas its 3 products are ADP, phosphate, and Ni2+. This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane…

Key takeaways

Nickel-transporting ATPase belongs to engineering; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Nickel-transporting ATPase to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Nickel-transporting ATPase from memory before moving on to harder problems.

Reference excerpt

In enzymology, a nickel-transporting ATPase (EC 3.6.3.24) is an enzyme that catalyzes the chemical reaction

ATP + H2O + Ni2+out ⇌ {\displaystyle \rightleftharpoons } ADP + phosphate + Ni2+in The 3 substrates of this enzyme are ATP, H2O, and Ni2+, whereas its 3 products are ADP, phosphate, and Ni2+. This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (nickel-importing).

Structural studies As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB: 1ZLQ and PDB: 2NOO.

References

Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146 (4): 271–8. doi:10.1016/0923-2508(96)81050-3. PMID 7569321. Hendricks JK, Mobley HL (1997). "Helicobacter pylori ABC transporter: effect of allelic exchange mutagenesis on urease activity". J. Bacteriol. 179 (18): 5892–902. doi:10.1128/jb.179.18.5892-5902.1997. PMC 179482. PMID 9294450. Saier MH (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. Advances in Microbial Physiology. 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 9780120277407. PMID 9889977.{{cite journal}}: CS1 maint: periodical has ISBN (link) Griffiths JK; Sansom CE. "The Transporter Factsbook, Academic Press, San Diego, 1998". {{cite journal}}: Cite journal requires |journal= (help)

Worked examples

Example 1 — a first encounter with Nickel-transporting ATPase

Start with the simplest possible case. Write down what Nickel-transporting ATPase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In engineering, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Nickel-transporting ATPase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Nickel-transporting ATPase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Nickel-transporting ATPase

In research: Nickel-transporting ATPase appears in engineering research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Nickel-transporting ATPase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Nickel-transporting ATPase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 3.6.3, EC 3.6 stubs, Enzymes of known structure, so understanding it makes those chapters shorter.
In everyday life: Look for Nickel-transporting ATPase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Nickel-transporting ATPase in 20 minutes

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Frequently asked questions

What is Nickel-transporting ATPase in simple terms?

In enzymology, a nickel-transporting ATPase (EC 3.6.3.24) is an enzyme that catalyzes the chemical reaction ATP + H2O + Ni2+out ⇌ {\displaystyle \rightleftharpoons } ADP + phosphate + Ni2+in The 3 substrates of this enzyme are ATP, H2O, and Ni2+, whereas its 3 products are ADP, phosphate, and Ni2+…

Why does Nickel-transporting ATPase matter?

Because it connects several engineering ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Nickel-transporting ATPase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Nickel-transporting ATPase.