Nicotinate riboside kinase (EC 2.7.1.173, ribosylnicotinic acid kinase, nicotinic acid riboside kinase, NRK1) is an enzyme with systematic name ATP:beta-D-ribosylnicotinate 5-phosphotransferase. It catalyses the following chemical reaction
This enzyme found in yeasts and humans converts D-ribosylnicotinate to nicotinate mononucleotide by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP). This is part of the biosynthetic pathway to nicotinamide adenine dinucleotide. An alternative substrate for the enzyme is nicotinamide riboside, similar to the enzyme ribosylnicotinamide kinase.
References
External links Nicotinate+riboside+kinase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)



