Night eating syndrome (NES) is classified as an Other Specified Feeding or Eating Disorder (OSFED) under the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). It involves recurrent episodes of night eating after awakening from sleep or after the evening meal. Awareness and recall of the eating is present, which is a key characteristic that differentiates the disorder from Sleep-Related Eating Disorder (SRED). Although there is some degree of comorbidity with binge eating disorder (BED), it differs from binge eating in that the amount of food consumed in the night is not necessarily objectively large nor is a loss of control over food intake required. The syndrome causes significant distress or functional impairment and cannot be better explained by external influences such as changes in the sleep-wake cycle, social norms, substance use, medication, or another mental or medical disorder.
History NES was originally described by Albert Stunkard in 1955 and is currently included in the other specified feeding or eating disorder (OSFED) category of the DSM-5. Most of the updated literature relating to NES has been published in recent years due to its recent changes in the DSM-5.
Epidemiology NES affects both men and women, between 1 and 2% of the general population, and approximately 10% of obese individuals. Newer research suggests that the overall prevalence of NES ranges from 2.8% to 15.2% in clinical patients with eating disorders, obesity, and/or bariatric surgery. Previously, the age of onset was typically in early adulthood (spanning from late teenage years to late twenties) and was often long-lasting, with children rarely reporting NES. However, newer studies have suggested that age is not a risk factor for NES, yet this evidence is still lacking. Other social-demographic factors such as income, gender, education level, children, living with a romantic partner, and smoking levels do not have an effect on NES. Furthermore, there have been contradictory conclusions on whether a higher BMI is a risk factor of NES, or if it is simply a consequence of night eating behavior. There has been no specific statistics regarding NES and mortality.
Comorbidities NES has a substantial association with medical diagnoses such as obesity, sleep apnea, hypercholesterolemia, polycystic ovarian syndrome, and diabetes mellitus type II (T2DM), and psychiatric diagnoses such as binge eating disorder, anorexia nervosa, bulimia nervosa, generalized anxiety disorder, major depressive disorder, and substance use disorders. In contrast to eating disorders like anorexia nervosa, NES does not necessarily depend on a person's Body Mass Index (BMI). It can occur in individuals with a weight considered normal for their age and height but is most commonly observed and studied in those with obesity. In fact, NES has been found to be a risk factor for an earlier onset of obesity. NES is most commonly comorbid with excess weight; as many as 28% of individuals seeking gastric bypass surgery were found to have NES in one study. Night eating syndrome has also been associated with diabetic complications. Many people with NES also experience depressed mood, post-traumatic stress disorder, and anxiety disorders. People with NES have been shown to have higher scores for depression and low self-esteem. NES may also have an association with personality traits, such as harm avoidance, self-directedness, and impulsivity. It has been demonstrated that nocturnal levels of the hormones melatonin and leptin are decreased. Individuals tend to have poorer sleep quality and higher levels of insomnia. Often times, people with NES are unaware of their condition due to it often being overshadowed by other comorbidities.
Diagnosis Specific research diagnostic criteria have been proposed outside of the DSM-5 and include: (A) Evening hyperphagia (consumption of 25% or more of the total daily calories after the evening meal) and/or nocturnal awakening and ingestion of food two or more times per week. (B) Awareness of the night eating to differentiate it from the parasomnia sleep-related eating disorder (SRED). (C) Three of five associated symptoms must also be present: lack of appetite in the morning, urges to eat at night, belief that one must eat in order to fall back to sleep at night, depressed mood, and/or difficulty sleeping. (D) The eating pattern causes significant distress or interferes with daily functioning. (E) The disordered pattern of eating has been maintained for at least 3 months. (F) The pattern is not attributable to substance use, medical conditions, medication, or another psychiatric disorder.
Testing When an eating disorder (ED) is suspected, health professionals should test using a validated tool: the Night Eating Questionnaire (NEQ), the Night Eating Diagnostic Questionnaire (NEDQ), the Eating Disorder Examination Questionnaire (EDE-Q), the Night Eating Syndrome History and Inventory (NESHI), or the Eating Among Teens Survey (EAT-II).
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