science

Nonsteroidal

Nonsteroidal is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Nonsteroidal rather than just read about it. In short: A nonsteroidal compound is a drug that is neither a steroid nor a steroid derivative. Nonsteroidal anti-inflammatory drugs (NSAIDs) are distinguished from corticosteroids as a class of anti-inflammatory agents.

Key takeaways

Nonsteroidal belongs to science; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Nonsteroidal to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Nonsteroidal from memory before moving on to harder problems.

Reference excerpt

A nonsteroidal compound is a drug that is neither a steroid nor a steroid derivative. Nonsteroidal anti-inflammatory drugs (NSAIDs) are distinguished from corticosteroids as a class of anti-inflammatory agents.

List of nonsteroidal steroid receptor modulators Examples include the following:

Estrogens: benzestrol, bifluranol, estrobin (DBE), diethylstilbestrol (stilbestrol), dienestrol, erteberel, fosfestrol, hexestrol (dihydroxystilbestrol), methallenestril, methestrol, methestrol dipropionate, paroxypropione, prinaberel, and triphenylethylene, as well as many xenoestrogens SERMsTooltip Selective estrogen receptor modulators: acolbifene, afimoxifene, arzoxifene, bazedoxifene, broparestrol, chlorotrianisene, clomifene, clomifenoxide, cyclofenil, droloxifene, enclomifene, endoxifen, ethamoxytriphetol, fispemifene, idoxifene, lasofoxifene, levormeloxifene, miproxifene, nafoxidine, nitromifene, ormeloxifene, ospemifene, panomifene, pipendoxifene, raloxifene, tamoxifen, toremifene, trioxifene, zindoxifene, zuclomifene Antiandrogens: apalutamide, bicalutamide, cimetidine, darolutamide, DIMP, enzalutamide, EPI-001, EPI-506, flutamide, hydroxyflutamide, inocoterone, inocoterone acetate, nilutamide, RU-58642, RU-58841, and topilutamide SARMsTooltip Selective androgen receptor modulators: AC-262,356, acetothiolutamide, andarine, BMS-564,929, enobosarm (ostarine), LGD-2226, LGD-3303, LGD-4033, S-23, and S-40503 Aromatase inhibitors: anastrozole, aminoglutethimide, fadrozole, finrozole, letrozole, liarozole, norendoxifen, rogletimide (pyridoglutethimide), vorozole Other steroidogenesis inhibitors: aminoglutethimide, ketoconazole, orteronel, seviteronel, others Miscellaneous: tanaproget (progestogen), finerenone (antimineralocorticoid), esaxerenone (antimineralocorticoid), apararenone (antimineralocorticoid), AZD5423 (glucocorticoid), mapracorat (SGRMTooltip Selective glucocorticoid receptor modulator)

See also Nonsteroidal antiandrogen Nonsteroidal estrogen

References

Further reading Miquel JF, Gilbert J (1988). "A chemical classification of nonsteroidal antagonists of sex-steroid hormone action". J. Steroid Biochem. 31 (4B): 525–44. doi:10.1016/0022-4731(88)90004-0. PMID 3059055. Buijsman, Rogier; Hermkens, Pedro; Rijn, Rachel; Stock, H.; Teerhuis, N. (2005). "Non-Steroidal Steroid Receptor Modulators". Current Medicinal Chemistry. 12 (9): 1017–1075. doi:10.2174/0929867053764671. ISSN 0929-8673. PMID 16821162. Hermkens PH, Kamp S, Lusher S, Veeneman GH (2006). "Non-steroidal steroid receptor modulators". IDrugs. 9 (7): 488–94. doi:10.2174/0929867053764671. PMID 16821162.

Worked examples

Example 1 — a first encounter with Nonsteroidal

Start with the simplest possible case. Write down what Nonsteroidal claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Nonsteroidal before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Nonsteroidal ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Nonsteroidal

In research: Nonsteroidal appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Nonsteroidal in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Nonsteroidal is common in secondary-school and first-year university syllabi. It links to neighbouring topics Pharmacology, Pharmacology stubs, so understanding it makes those chapters shorter.
In everyday life: Look for Nonsteroidal outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Nonsteroidal in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Nonsteroidal means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Nonsteroidal out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Nonsteroidal in simple terms?

Why does Nonsteroidal matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Nonsteroidal?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Nonsteroidal.