science

Ortho-McNeil Pharmaceutical

Ortho-McNeil Pharmaceutical is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Ortho-McNeil Pharmaceutical rather than just read about it. In short: Ortho-McNeil Pharmaceutical (now operating under Janssen Pharmaceuticals) was a pharmaceutical company based in Raritan, New Jersey, that was formed from the merger of Ortho Pharmaceutical and McNeil Pharmaceutical in 1993. These pharmaceutical companies were pioneers and leaders in areas such as pain management, acid reflux disease, and infectious diseases.

Key takeaways

Ortho-McNeil Pharmaceutical belongs to science; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Ortho-McNeil Pharmaceutical to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Ortho-McNeil Pharmaceutical from memory before moving on to harder problems.

Reference excerpt

Ortho-McNeil Pharmaceutical (now operating under Janssen Pharmaceuticals) was a pharmaceutical company based in Raritan, New Jersey, that was formed from the merger of Ortho Pharmaceutical and McNeil Pharmaceutical in 1993. These pharmaceutical companies were pioneers and leaders in areas such as pain management, acid reflux disease, and infectious diseases. Ortho-McNeil and Janssen Pharmaceuticals together composed the Ortho-McNeil-Janssen group within Johnson & Johnson before a decision to operate under the Janssen Pharmaceuticals name in 2011.

Products Amongst its many prescription drugs are:

Ortho Tri-cyclen Ortho-Evra Doribax Elmiron Levaquin Ultram ER Aciphex Concerta

Lawsuits

Topamax

False claims federal case In 2010, Ortho-McNeil pled guilty in U.S. District Court to one count of misdemeanor violation of the Food, Drug & Cosmetic Act for illegally promoting its epilepsy drug Topamax for uses that were not approved by the FDA. The company was charged with using a program called "Doctor for a Day" to promote Topamax to psychiatrists for treatment of mental health conditions, despite never applying for FDA approval of Topimax for any psychiatric indication. The company was sentenced to pay a fine of $6.14 million. Ortho-McNeil's parent company, Johnson and Johnson, also paid $75.37 million to resolve civil allegations under the False Claims Act that it caused false claims to be submitted to government health care programs for a variety of psychiatric uses that were not FDA approved.

Civil lawsuits Ortho-McNeil was found liable in two 2013 civil suits by women who gave birth to children with birth defects after taking Topamax while pregnant. The jury found that they negligently failed to warn the patients and their doctors of the risks associated with Topamax when used by patients during pregnancy. They awarded $11 million in damages to one family and $4 million to the other. As a result of these and other patient reports, the FDA ordered that a warning be added to the prescribing information for Topamax detailing the risk of birth defects such as cleft lip and cleft palate.

See also Biotech and pharmaceutical companies in the New York metropolitan area Cilag Janssen Pharmaceutica

References

External links Official website

Worked examples

Example 1 — a first encounter with Ortho-McNeil Pharmaceutical

Start with the simplest possible case. Write down what Ortho-McNeil Pharmaceutical claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Ortho-McNeil Pharmaceutical before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Ortho-McNeil Pharmaceutical ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Ortho-McNeil Pharmaceutical

In research: Ortho-McNeil Pharmaceutical appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Ortho-McNeil Pharmaceutical in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Ortho-McNeil Pharmaceutical is common in secondary-school and first-year university syllabi. It links to neighbouring topics American companies established in 1993, Companies based in New Jersey, Johnson & Johnson subsidiaries, so understanding it makes those chapters shorter.
In everyday life: Look for Ortho-McNeil Pharmaceutical outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

Ask Teacher Smith questions about this articleOpens your AI tutor with a question about “Ortho-McNeil Pharmaceutical” →

Affiliate

Preply — study more efficiently by working with a personal tutor. 50% off.

How to study Ortho-McNeil Pharmaceutical in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Ortho-McNeil Pharmaceutical means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Ortho-McNeil Pharmaceutical out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Ortho-McNeil Pharmaceutical in simple terms?

Why does Ortho-McNeil Pharmaceutical matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Ortho-McNeil Pharmaceutical?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Ortho-McNeil Pharmaceutical.