chemistry

Oxprenolol

Oxprenolol is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Oxprenolol rather than just read about it. In short: Oxprenolol, sold under the brand name Trasicor among others, is a non-selective beta blocker with some intrinsic sympathomimetic activity. It was used for the treatment of angina pectoris, abnormal heart rhythms, and high blood pressure.

Key takeaways

Oxprenolol belongs to chemistry; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Oxprenolol to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Oxprenolol from memory before moving on to harder problems.

Reference excerpt

Oxprenolol, sold under the brand name Trasicor among others, is a non-selective beta blocker with some intrinsic sympathomimetic activity. It was used for the treatment of angina pectoris, abnormal heart rhythms, and high blood pressure.

Medical uses Oxprenolol has been used in the treatment of angina pectoris, abnormal heart rhythms, and high blood pressure. It has been used to treat anxiety as well.

Contraindications Oxprenolol is a potent beta blocker and should not be administered to asthmatics under any circumstances due to their low beta levels as a result of depletion due to other asthma medication, and because it can cause irreversible, often fatal, airway failure and inflammation.

Pharmacology

Pharmacodynamics Oxprenolol is a beta blocker. In addition, it has been found to act as an antagonist of the serotonin 5-HT1A and 5-HT1B receptors with respective Ki values of 94.2 nM and 642 nM in rat brain tissue.

Pharmacokinetics Oxprenolol is a lipophilic beta blocker which passes the blood–brain barrier more easily than hydrophilic beta blockers. As such, it is associated with a higher incidence of CNS-related side effects than beta blockers with more hydrophilic molecules such as atenolol, sotalol, and nadolol. The brain-to-blood ratio of oxprenolol in humans has been found to be 50:1. For comparison, the brain-to-blood ratio of the highly lipophilic propranolol was 15:1 to 26:1 and of the hydrophilic atenolol was 0.2:1.

Chemistry The experimental log P of oxprenolol is 2.10.

Stereochemistry Oxprenolol is a chiral compound, the beta blocker is used as a racemate, e. g. a 1:1 mixture of (R)-(+)-oxprenolol and (S)-(–)-oxprenolol. Analytical methods (HPLC) for the separation and quantification of (R)-(+)-oxprenolol and (S)-(–)-oxprenolol in urine and in pharmaceutical formulations have been described in the literature.

Society and culture

Brand names Brand names of oxprenolol include Trasacor, Trasicor, Coretal, Laracor, Slow-Pren, Captol, Corbeton, Slow-Trasicor, Tevacor, Trasitensin, and Trasidex.

References

Illustrations

Worked examples

Example 1 — a first encounter with Oxprenolol

Start with the simplest possible case. Write down what Oxprenolol claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Oxprenolol before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Oxprenolol ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Oxprenolol

In research: Oxprenolol appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Oxprenolol in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Oxprenolol is common in secondary-school and first-year university syllabi. It links to neighbouring topics 5-HT1A antagonists, 5-HT1B antagonists, Allyl compounds, so understanding it makes those chapters shorter.
In everyday life: Look for Oxprenolol outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

Ask Teacher Smith questions about this articleOpens your AI tutor with a question about “Oxprenolol” →

Affiliate

Preply — study more efficiently by working with a personal tutor. 50% off.

How to study Oxprenolol in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Oxprenolol means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Oxprenolol out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Oxprenolol in simple terms?

Why does Oxprenolol matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Oxprenolol?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Oxprenolol.