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biology

PEA15

PEA15 is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand PEA15 rather than just read about it. In short: Astrocytic phosphoprotein PEA-15 is a protein that in humans is encoded by the PEA15 gene. PEA15 is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes.

PEA15 — main illustration
PEA15 — illustration

Key takeaways

  • PEA15 belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect PEA15 to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of PEA15 from memory before moving on to harder problems.

Reference excerpt

Astrocytic phosphoprotein PEA-15 is a protein that in humans is encoded by the PEA15 gene. PEA15 is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes. PEA-15 promotes autophagy in glioma cells in a JNK-dependent manner.

Interactions PEA15 has been shown to interact with:

Caspase 8, FADD, and MAPK1, Phospholipase D1, and RPS6KA3.

References

Further reading

Illustrations

PEA15 illustration
PEA15 illustration
PEA15 illustration
PEA15 illustration
PEA15 illustration

Worked examples

Example 1 — a first encounter with PEA15

Start with the simplest possible case. Write down what PEA15 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to PEA15 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about PEA15 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of PEA15

In research
PEA15 appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses PEA15 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
PEA15 is common in secondary-school and first-year university syllabi. It links to neighbouring topics Genes on human chromosome 1, Human chromosome 1 gene stubs, so understanding it makes those chapters shorter.
In everyday life
Look for PEA15 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study PEA15 in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what PEA15 means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain PEA15 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is PEA15 in simple terms?

Astrocytic phosphoprotein PEA-15 is a protein that in humans is encoded by the PEA15 gene. PEA15 is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes.

Why does PEA15 matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study PEA15?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on PEA15.

Tags

  • Genes on human chromosome 1
  • Human chromosome 1 gene stubs

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