Peroxisomal trans-2-enoyl-CoA reductase is an enzyme that in humans is encoded by the PECR gene. Research suggests that the (human) enzyme participates in the conversion of phytol to phytanic acid in the peroxisomes, which is part of the process of breaking down phytol. In particular, it catalyzes reactions of the form:
a (2E)-enoyl-CoA + NADPH + H+ ⇌ {\displaystyle \rightleftharpoons } a 2,3-saturated acyl-CoA + NADP+ With affinity for trans-2-enoyl-CoAs of lengths between 4:1 and 16:1.
See Also MECR
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